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ALOX5 抗体

ALOX5 适用: 人, 大鼠, 小鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7234612
发货至: 中国
  • 抗原 See all ALOX5 抗体
    ALOX5 (Arachidonate 5-Lipoxygenase (ALOX5))
    适用
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    人, 大鼠, 小鼠
    宿主
    • 103
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    • 1
    克隆类型
    • 102
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    多克隆
    标记
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    This ALOX5 antibody is un-conjugated
    应用范围
    • 62
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    Immunohistochemistry (IHC), ELISA
    产品特性
    Polyclonal Antibody
    纯化方法
    Affinity purification
    免疫原
    Recombinant protein of human ALOX5
    亚型
    IgG
    Top Product
    Discover our top product ALOX5 Primary Antibody
  • 应用备注
    IHC 1:50-1:150
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.7 mg/mL
    缓冲液
    PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    ALOX5 (Arachidonate 5-Lipoxygenase (ALOX5))
    别名
    ALOX5 (ALOX5 产品)
    别名
    5-LO antibody, 5-LOX antibody, 5LPG antibody, LOG5 antibody, 5LO antibody, 5LX antibody, AI850497 antibody, F730011J02 antibody, LOX5A antibody, si:dkey-194n13.2 antibody, lox5 antibody, arachidonate 5-lipoxygenase antibody, arachidonate 5-lipoxygenase a antibody, Arachidonate 5-lipoxygenase antibody, ALOX5 antibody, Alox5 antibody, alox5a antibody, AFUA_4G02770 antibody, AOR_1_1362014 antibody, lox5 antibody
    背景
    This gene encodes a member of the lipoxygenase gene family and plays a dual role in the synthesis of leukotrienes from arachidonic acid. The encoded protein, which is expressed specifically in bone marrow-derived cells, catalyzes the conversion of arachidonic acid to 5(S)-hydroperoxy-6-trans-8,11,14-cis-eicosatetraenoic acid, and further to the allylic epoxide 5(S)-trans-7,9-trans-11,14-cis-eicosatetrenoic acid (leukotriene A4). Leukotrienes are important mediators of a number of inflammatory and allergic conditions. Mutations in the promoter region of this gene lead to a diminished response to antileukotriene drugs used in the treatment of asthma and may also be associated with atherosclerosis and several cancers. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
    UniProt
    P09917
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