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DDR1 抗体 (C-Term)

DDR1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3044099
发货至: 中国
  • 抗原 See all DDR1 抗体
    DDR1 (Discoidin Domain Receptor tyrosine Kinase 1 (DDR1))
    抗原表位
    • 20
    • 15
    • 10
    • 7
    • 7
    • 7
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
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    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 898-913, C-Term
    适用
    • 87
    • 43
    • 43
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    宿主
    • 94
    • 8
    克隆类型
    • 93
    • 8
    • 1
    多克隆
    标记
    • 49
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This DDR1 antibody is un-conjugated
    应用范围
    • 81
    • 42
    • 26
    • 26
    • 24
    • 13
    • 10
    • 6
    • 5
    • 5
    • 4
    • 2
    • 1
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    Western Blotting (WB)
    原理
    Rabbit IgG polyclonal antibody for Epithelial discoidin domain-containing receptor 1(DDR1) detection. Tested with WB in Human,Rat.
    序列
    FSQLHRFLAE DALNTV
    交叉反应 (详细)
    Predicted Cross Reactivity: rat
    No cross reactivity with other proteins.
    Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.
    产品特性
    Rabbit IgG polyclonal antibody for Epithelial discoidin domain-containing receptor 1(DDR1) detection. Tested with WB in Human,Rat.
    Gene Name: discoidin domain receptor tyrosine kinase 1
    Protein Name: Epithelial discoidin domain-containing receptor 1
    纯化方法
    Immunogen affinity purified.
    免疫原
    A synthetic peptide corresponding to a sequence at the C-terminus of human MCK10(898-913aa FSQLHRFLAEDALNTV), different from the related rat sequence by one amino acid, and from the related mouse sequence by two amino acids.
    亚型
    IgG
    Top Product
    Discover our top product DDR1 Primary Antibody
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Predicted Species: Rat, The detection limit for DDR1 is approximately 0.5 ng/lane under reducing conditions.
    Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
    Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
    储存液
    Thimerosal (Merthiolate), Sodium azide
    注意事项
    This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
    有效期
    12 months
  • 抗原
    DDR1 (Discoidin Domain Receptor tyrosine Kinase 1 (DDR1))
    别名
    DDR1 (DDR1 产品)
    别名
    CG11573 antibody, CG13984 antibody, CG13985 antibody, CG33531 antibody, CG9488 antibody, CG9490 antibody, CT33540 antibody, DDR antibody, Dmel\\CG33531 antibody, Dmel_CG13984 antibody, 6030432F18 antibody, AI323681 antibody, CD167a antibody, Cak antibody, Nep antibody, PTK3A antibody, CAK antibody, CD167 antibody, EDDR1 antibody, HGK2 antibody, MCK10 antibody, NEP antibody, NTRK4 antibody, PTK3 antibody, RTK6 antibody, TRKE antibody, Drd1 antibody, PTK3D antibody, Discoidin domain receptor antibody, discoidin domain receptor family, member 1 antibody, discoidin domain receptor tyrosine kinase 1 antibody, Ddr antibody, Ddr1 antibody, DDR1 antibody
    背景
    DDR1(Discoidin domain receptor family, member 1) also known as NEP, EDDR1, NTRK4, TRKE, DDR, CAK or RTK6, is a human gene. The protein encoded by this gene is a RTK that is widely expressed in normal and transformed epithelial cells and is activated by various types of collagen.This protein belongs to a subfamily of tyrosine kinase receptors with a homology region to the Dictyostelium discoideum protein discoidin I in their extracellular domain.The DDR1 gene is mapped on 6p21.33. The fibrillar collagens and immobilized collagen activated DDR1 receptor phosphorylation after prolonged treatment. Bhatt et al.(2000) showed that Ddr1 was highly expressed in the cerebellum of developing and adult mouse brain, and that both Ddr1 and collagen IV were highly expressed in the pial layer of the cerebellar cortex. Cocultures of collagen I- and IV-expressing mouse pial cells with Ddr1-expressing granule cells resulted in granule cell neurite extension. Inhibition of collagen-Ddr1signaling reduced granule cell neurite elongation.

    Synonyms: CAK antibody|CD 167 antibody|CD167 antibody|CD167 antigen-like family member A antibody|CD167a antibody|Cell adhesion kinase antibody|DDR 1 antibody|DDR antibody|DDR1 antibody|DDR1_HUMAN antibody|Discoidin domain receptor antibody|Discoidin domain receptor tyrosine kinase 1 antibody|Discoidin receptor tyrosine kinase antibody|Discoidin receptor tyrosine kinase isoform a antibody|EDDR 1 antibody|EDDR1 antibody|Epithelial discoidin domain receptor 1 antibody|Epithelial discoidin domain-containing receptor 1 antibody|Epithelial specific receptor kinase antibody|HGK2 antibody|Mammarian carcinoma kinase 10 antibody|Mammary carcinoma kinase 10 antibody|MCK-10 antibody|MCK10 antibody|NEP antibody|Neuroepithelial tyrosine kinase antibody|Neurotrophic tyrosine kinase receptor type 4 antibody|NTRK 4 antibody|NTRK4 antibody|OTTHUMP00000029343 antibody|OTTHUMP00000029344 antibody|OTTHUMP00000029345 antibody|OTTHUMP00000029346 antibody|OTTHUMP00000029347 antibody|OTTHUMP00000164863 antibody|OTTHUMP00000164867 antibody|OTTHUMP00000222080 antibody|Protein-tyrosine kinase 3A antibody|Protein-tyrosine kinase RTK-6 antibody|PTK 3 antibody|PTK 3A protein tyrosine kinase 3A antibody|PTK3 antibody|PTK3A antibody|Receptor tyrosine kinase NEP antibody|RTK 6 antibody|RTK6 antibody|TRK E antibody|TRKE antibody|Tyrosine kinase DDR antibody|Tyrosine kinase receptor E antibody|Tyrosine-protein kinase CAK antibody
    UniProt
    Q08345
    途径
    RTK signaling, Smooth Muscle Cell Migration
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