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DDR1 抗体 (AA 396-430)

DDR1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB50593 unconjugated
产品编号 ABIN6243407
发货至: 中国
  • 抗原 See all DDR1 抗体
    DDR1 (Discoidin Domain Receptor tyrosine Kinase 1 (DDR1))
    抗原表位
    • 20
    • 15
    • 10
    • 7
    • 7
    • 7
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 396-430
    适用
    • 87
    • 43
    • 42
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    人, 小鼠
    宿主
    • 93
    • 9
    克隆类型
    • 92
    • 9
    • 1
    多克隆
    标记
    • 49
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This DDR1 antibody is un-conjugated
    应用范围
    • 81
    • 43
    • 26
    • 26
    • 24
    • 14
    • 10
    • 6
    • 5
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    预测反应
    Rat
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This Mouse Ddr1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 396-430 amino acids from the Central region of human Mouse Ddr1.
    克隆位点
    RB50593
    亚型
    Ig Fraction
    Top Product
    Discover our top product DDR1 Primary Antibody
  • 应用备注
    WB: 1:1000. WB: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    有效期
    6 months
  • 抗原
    DDR1 (Discoidin Domain Receptor tyrosine Kinase 1 (DDR1))
    别名
    Ddr1 (DDR1 产品)
    别名
    CG11573 antibody, CG13984 antibody, CG13985 antibody, CG33531 antibody, CG9488 antibody, CG9490 antibody, CT33540 antibody, DDR antibody, Dmel\\CG33531 antibody, Dmel_CG13984 antibody, 6030432F18 antibody, AI323681 antibody, CD167a antibody, Cak antibody, Nep antibody, PTK3A antibody, CAK antibody, CD167 antibody, EDDR1 antibody, HGK2 antibody, MCK10 antibody, NEP antibody, NTRK4 antibody, PTK3 antibody, RTK6 antibody, TRKE antibody, Drd1 antibody, PTK3D antibody, Discoidin domain receptor antibody, discoidin domain receptor family, member 1 antibody, discoidin domain receptor tyrosine kinase 1 antibody, Ddr antibody, Ddr1 antibody, DDR1 antibody
    背景
    Tyrosine kinase that functions as cell surface receptor for fibrillar collagen and regulates cell attachment to the extracellular matrix, remodeling of the extracellular matrix, cell migration, differentiation, survival and cell proliferation. Collagen binding triggers a signaling pathway that involves SRC and leads to the activation of MAP kinases. Regulates remodeling of the extracellular matrix by up-regulation of the matrix metalloproteinases MMP2, MMP7 and MMP9, and thereby facilitates cell migration and wound healing, but also tumor cell invasion. Promotes smooth muscle cell migration, and thereby contributes to arterial wound healing. Phosphorylates PTPN11 (By similarity). Required for normal blastocyst implantation during pregnancy, for normal mammary gland differentiation and normal lactation. Required for normal ear morphology and normal hearing.
    分子量
    101161
    UniProt
    Q03146
    途径
    RTK signaling, Smooth Muscle Cell Migration
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