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XRCC6 抗体 (C-Term)

Name: XRCC6 抗体 (C-Term)
SKU: ABIN3043965
Availability: OutOfStock

XRCC6 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

Western Blotting (WB) image for anti-X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 (XRCC6) (AA 464-496), (C-Term) antibody (ABIN3043965) (XRCC6 抗体 (C-Term))

Anti- Ku70 Picoband antibody, IHC(P) IHC(P): Human Tonsil Tissue (XRCC6 抗体 (C-Term))

IHC

2 images

产品编号 ABIN3043965

发货至: 中国

Datasheet as PDF

抗原 See all XRCC6 抗体

XRCC6 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 (XRCC6))
抗原表位
13

9

8

8

8

8

7

6

6

6

4

4

3

3

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 464-496, C-Term
适用
141

40

24

9

2

2

1

1

1

1

1

1

1

1
人
宿主
122

20

2
兔
Compatible Secondaries
克隆类型
115

28
多克隆
标记
93

8

7

7

6

5

3

3

3

3

3

3
This XRCC6 antibody is un-conjugated
应用范围
115

78

72

49

44

23

20

14

4

2

2

2

2

1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

原理

Rabbit IgG polyclonal antibody for X-ray repair cross-complementing protein 6(XRCC6) detection. Tested with WB, IHC-P in Human.

序列

AIVEKLRFTY RSDSFENPVL QQHFRNLEAL ALD

交叉反应（详细）

No cross reactivity with other proteins.

产品特性

Rabbit IgG polyclonal antibody for X-ray repair cross-complementing protein 6(XRCC6) detection. Tested with WB, IHC-P in Human.
Gene Name: X-ray repair complementing defective repair in Chinese hamster cells 6
Protein Name: X-ray repair cross-complementing protein 6

纯化方法

Immunogen affinity purified.

免疫原

A synthetic peptide corresponding to a sequence at C-terminus of human Ku70 (464-496aa AIVEKLRFTYRSDSFENPVLQQHFRNLEALALD), different from the related mouse sequence by one amino acid.

亚型

IgG

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anti-X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 (XRCC6) (AA 1-609) antibody
XRCC6 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 4C2-1A6 unconjugated

anti-X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 (XRCC6) (AA 500-600) antibody
XRCC6 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 (XRCC6) (C-Term) antibody
XRCC6 适用: 人 WB, IF, IHC (p), IP, ICC, PLA 宿主: 兔 Polyclonal unconjugated

anti-X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 (XRCC6) (AA 319-538) antibody
XRCC6 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 (XRCC6) (AA 397-603) antibody
XRCC6 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 (XRCC6) antibody
XRCC6 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 (XRCC6) (Ser404) antibody
XRCC6 适用: 人 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 (XRCC6) (acLys542) antibody
XRCC6 适用: 人 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 (XRCC6) (AA 408-609) antibody
XRCC6 适用: 人 WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated

anti-X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 (XRCC6) (AA 6-214) antibody
XRCC6 适用: 人 WB, ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 2F7F5 unconjugated

应用备注

WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

说明

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C/-20 °C

储存方法

At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
抗原

XRCC6 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 (XRCC6))

别名

XRCC6 (XRCC6 产品)

别名

CTC75 antibody, CTCBF antibody, G22P1 antibody, KU70 antibody, ML8 antibody, TLAA antibody, 70kDa antibody, G22p1 antibody, Ku70 antibody, Kup70 antibody, X-ray repair cross complementing 6 antibody, ATP-dependent DNA helicase II, 70 kDa subunit antibody, X-ray repair complementing defective repair in Chinese hamster cells 6 L homeolog antibody, X-ray repair complementing defective repair in Chinese hamster cells 6 antibody, XRCC6 antibody, Bm1_41430 antibody, xrcc6.L antibody, Xrcc6 antibody

背景

XRCC6 (X-Ray Repair, Complementing Defective, In Chinese Hamster, 6), also called Ku70, G22P1 or TLAA, is a protein that in humans, is encoded by the XRCC6 gene. In addition, the XRCC6 gene encodes subunit p70 of the p70/p80 autoantigen which consists of 2 proteins of molecular mass of approximately 70,000 and 80,000 daltons that dimerize to form a 10 S DNA-binding complex. The XRCC6 gene is mapped to 22q13.2. XRCC6 and Mre11 are differentially expressed during meiosis. XRCC6 interacts with Baxa, a mediator of mitochondrial-dependent apoptosis. Disruption of both FANCC and XRCC6 suppressed sensitivity to crosslinking agents, diminished chromosome breaks, and reversed defective homologous recombination. Ku70 binds directly to free DNA ends, committing them to NHEJ repair. In early meiotic prophase, however, when meiotic recombination is most probably initiated, Mre11 was abundant, whereas XRCC6 was not detectable.

Synonyms: 5''-deoxyribose-5-phosphate lyase Ku70 antibody|5''-dRP lyase Ku70 antibody|70 kDa subunit of Ku antigen antibody|ATP dependent DNA helicase 2 subunit 1 antibody|ATP dependent DNA helicase II 70 kDa subunit antibody|ATP-dependent DNA helicase 2 subunit 1 antibody|ATP-dependent DNA helicase II 70 kDa subunit antibody|CTC box binding factor 75 kDa subunit antibody|CTC box-binding factor 75 kDa subunit antibody|CTC75 antibody|CTCBF antibody|DNA repair protein XRCC6 antibody|G22P1 antibody|Ku 70 antibody|Ku autoantigen 70 kDa antibody| Ku autoantigen p70 subunit antibody|Ku autoantigen, 70 kDa antibody|Ku p70 antibody|Ku70 antibody|Ku70 DNA binding component of DNA-dependent proteinkinase complex (thyroid autoantigen 70 kDa antibody|Kup70 antibody|Lupus Ku autoantigen protein p70 antibody|ML8 antibody|Thyroid autoantigen 70kD (Ku antigen) antibody|Thyroid autoantigen antibody| Thyroid lupus autoantigen antibody|Thyroid lupus autoantigen p70 antibody|Thyroid-lupus autoantigen antibody|TLAA antibody|X ray repair complementing defective repair in Chinese hamster cells 6 antibody|X-ray repair complementing defective repair in Chinese hamster cells 6 antibody|X-ray repair cross-complementing protein 6 antibody|XRCC 6 antibody|XRCC6 antibody|XRCC6_HUMAN antibody

基因ID

2547

UniProt

P12956

途径

DNA Damage Repair