电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

RIPK1 抗体 (Middle Region)

RIPK1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3042930
发货至: 中国
  • 抗原 See all RIPK1 抗体
    RIPK1 (Receptor (TNFRSF)-Interacting serine-threonine Kinase 1 (RIPK1))
    抗原表位
    • 16
    • 8
    • 7
    • 7
    • 7
    • 6
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 411-425, Middle Region
    适用
    • 87
    • 39
    • 28
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    宿主
    • 83
    • 11
    克隆类型
    • 74
    • 20
    多克隆
    标记
    • 38
    • 9
    • 8
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This RIPK1 antibody is un-conjugated
    应用范围
    • 63
    • 33
    • 20
    • 15
    • 13
    • 13
    • 12
    • 12
    • 5
    • 4
    • 3
    • 2
    • 1
    Western Blotting (WB)
    原理
    Rabbit IgG polyclonal antibody for Receptor-interacting serine/threonine-protein kinase 1(RIPK1) detection. Tested with WB in Human.
    序列
    RRRRVSHDPF AQQRP
    交叉反应 (详细)
    No cross reactivity with other proteins.
    产品特性
    Rabbit IgG polyclonal antibody for Receptor-interacting serine/threonine-protein kinase 1(RIPK1) detection. Tested with WB in Human.
    Gene Name: receptor(TNFRSF)-interacting serine-threonine kinase 1
    Protein Name: Receptor-interacting serine/threonine-protein kinase 1
    纯化方法
    Immunogen affinity purified.
    免疫原
    A synthetic peptide corresponding to a sequence in the middle region of human RIP(411-425aa RRRRVSHDPFAQQRP).
    亚型
    IgG
    Top Product
    Discover our top product RIPK1 Primary Antibody
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, The detection limit for RIPK1 is approximately 1 ng/lane under reducing conditions.
    Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
    Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
    储存液
    Thimerosal (Merthiolate), Sodium azide
    注意事项
    This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
    有效期
    12 months
  • Wang, Ma, Hu, Xie, Wu, Zeng, Song: "Bifidobacterial recombinant thymidine kinase-ganciclovir gene therapy system induces FasL and TNFR2 mediated antitumor apoptosis in solid tumors." in: BMC cancer, Vol. 16, pp. 545, (2017) (PubMed).

    Chen, Zhao, Wu, Zou, Luo, Li, Xie, Liang: "The role of RIP1 and RIP3 in the development of aplastic anemia induced by cyclophosphamide and busulphan in mice." in: International journal of clinical and experimental pathology, Vol. 7, Issue 12, pp. 8411-20, (2015) (PubMed).

  • 抗原
    RIPK1 (Receptor (TNFRSF)-Interacting serine-threonine Kinase 1 (RIPK1))
    别名
    RIPK1 (RIPK1 产品)
    别名
    RIP antibody, RIP1 antibody, D330015H01Rik antibody, Rinp antibody, Rip1 antibody, rip1 antibody, ripk1 antibody, xRIP1beta antibody, xrip1 antibody, receptor interacting serine/threonine kinase 1 antibody, receptor (TNFRSF)-interacting serine-threonine kinase 1 antibody, receptor interacting serine/threonine kinase 1 L homeolog antibody, RIPK1 antibody, Ripk1 antibody, ripk1.L antibody
    背景
    RIPK1(Regulator of G Protein Signaling 3), also called RIP, is an enzyme that in humans is encoded by the RIPK1 gene. Members of the TRAF protein family have been implicated in the activation of NF-kappa-B by the TNF superfamily. By yeast 2-hybrid and coimmunoprecipitation studies using mammalian cell extracts, Hsu et al.(1996) showed that RIP interacts with TRADD, TRAF1, TRAF2, and TRAF3. Hartz(2012) mapped the RIPK1 gene to chromosome 6p25.2 based on an alignment of the RIPK1 sequence with the genomic sequence. Stanger et al.(1995) found that overexpression of Rip in mammalian cells induced morphologic changes characteristic of apoptosis. They suggested that RIP may be an important element in the signal transduction machinery that mediates programmed cell death.

    Synonyms: Cell death protein RIP antibody|FLJ39204 antibody|OTTHUMP00000039163 antibody|Receptor(TNFRSF) interacting serine threonine kinase 1 antibody|receptor interacting protein 1 antibody|Receptor interacting protein antibody|Receptor interacting serine threonine protein kinase 1 antibody|Receptor TNFRSF interacting serine threonine kinase 1 antibody|Receptor-interacting protein 1 antibody|Receptor-interacting serine/threonine-protein kinase 1 antibody|Rinp antibody|RIP 1 antibody|RIP antibody|Rip-1 antibody|RIP1 antibody|RIPK 1 antibody|RIPK1 antibody|RIPK1_HUMAN antibody|Serine threonine protein kinase RIP antibody|Serine/threonine-protein kinase RIP antibody
    UniProt
    Q13546
    途径
    NF-kappaB Signaling, Apoptosis, Caspase Cascade in Apoptosis, TLR signaling, Activation of Innate immune Response, Inositol Metabolic Process, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Negative Regulation of intrinsic apoptotic Signaling, SARS-CoV-2 Protein Interactome, Ubiquitin Proteasome Pathway
You are here:
客服