Immunohistochemistry on Paraffin Sections (5-10 μg/mL). ELISA (1/32000). Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
限制
仅限研究用
浓度
0.5 mg/mL
缓冲液
Tris buffered saline containing 0.5 % BSA and 0.02 % sodium azide as preservative.
储存液
Sodium azide
注意事项
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项
Avoid cycles of freezing and thawing.
储存条件
-20 °C
储存方法
Store the antibody (in aliquots) at-20 °C. Dilute only prior to immediate use.
抗原
SCN5A
(Sodium Channel, Voltage-Gated, Type V, alpha Subunit (SCN5A))
Scn5a encodes the alpha subunit of the type V voltage-gated sodium channel. These channels, composed of one alpha and one or two beta subunits, mediate changes in cell permeability to sodium ions that are essential for the generation of action potentials. The alpha subunit alone has been shown to generate a functional channel in vitro, but it's kinetic properties are modulated by beta subunits. The type V channel has been shown to be tetrodotoxin-resistant. Scn5a null mice experience intrauterine lethality. Mutations in the SCN5A gene are responsible for several heart conditions, including the chromosome 3-linked form of long LQT and Brugada syndrome.Synonyms: CDCD2, HB1, HB2, HBBD, HH1, LQT3, Nav1.5, Sodium channel protein cardiac muscle subunit alpha, Sodium channel protein type 5 subunit alpha, Sodium channel protein type V subunit alpha, Voltage-gated sodium channel subunit alpha Nav1.5