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SCN5A 抗体 (Internal Region)

SCN5A 适用: 人 IHC (p), EIA 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN303416
发货至: 中国
  • 抗原 See all SCN5A 抗体
    SCN5A (Sodium Channel, Voltage-Gated, Type V, alpha Subunit (SCN5A))
    抗原表位
    • 14
    • 8
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Internal Region
    适用
    • 34
    • 16
    • 16
    • 5
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 33
    • 2
    • 1
    山羊
    克隆类型
    • 36
    多克隆
    标记
    • 19
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SCN5A antibody is un-conjugated
    应用范围
    • 26
    • 18
    • 8
    • 2
    • 1
    • 1
    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    特异性
    This antibody recognises SCN5A.
    纯化方法
    Immunoaffinity Chromatography.
    免疫原
    Amino Acids (C)ETDDQSPEKIN from an internal region of human SCN5A.
    Top Product
    Discover our top product SCN5A Primary Antibody
  • 应用备注
    Immunohistochemistry on Paraffin Sections (5-10 μg/mL). ELISA (1/32000).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Tris buffered saline containing 0.5 % BSA and 0.02 % sodium azide as preservative.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid cycles of freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Store the antibody (in aliquots) at-20 °C. Dilute only prior to immediate use.
  • 抗原
    SCN5A (Sodium Channel, Voltage-Gated, Type V, alpha Subunit (SCN5A))
    别名
    SCN5A (SCN5A 产品)
    别名
    Nav1.5 antibody, Nav1.5c antibody, SkM1 antibody, SkM2 antibody, mH1 antibody, CDCD2 antibody, CMD1E antibody, CMPD2 antibody, HB1 antibody, HB2 antibody, HBBD antibody, HH1 antibody, ICCD antibody, IVF antibody, LQT3 antibody, PFHB1 antibody, SSS1 antibody, VF1 antibody, SCAL antibody, sodium voltage-gated channel alpha subunit 5 antibody, sodium channel, voltage-gated, type V, alpha antibody, SCN5A antibody, Scn5a antibody
    背景
    Scn5a encodes the alpha subunit of the type V voltage-gated sodium channel. These channels, composed of one alpha and one or two beta subunits, mediate changes in cell permeability to sodium ions that are essential for the generation of action potentials. The alpha subunit alone has been shown to generate a functional channel in vitro, but it's kinetic properties are modulated by beta subunits. The type V channel has been shown to be tetrodotoxin-resistant. Scn5a null mice experience intrauterine lethality. Mutations in the SCN5A gene are responsible for several heart conditions, including the chromosome 3-linked form of long LQT and Brugada syndrome.Synonyms: CDCD2, HB1, HB2, HBBD, HH1, LQT3, Nav1.5, Sodium channel protein cardiac muscle subunit alpha, Sodium channel protein type 5 subunit alpha, Sodium channel protein type V subunit alpha, Voltage-gated sodium channel subunit alpha Nav1.5
    基因ID
    6331
    NCBI登录号
    NP_000326
    UniProt
    Q14524
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