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SCN5A 抗体

SCN5A 适用: 人 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7182719
发货至: 中国
  • 抗原 See all SCN5A 抗体
    SCN5A (Sodium Channel, Voltage-Gated, Type V, alpha Subunit (SCN5A))
    适用
    • 33
    • 16
    • 16
    • 5
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    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 32
    • 2
    • 1
    克隆类型
    • 35
    多克隆
    标记
    • 18
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
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    This SCN5A antibody is un-conjugated
    应用范围
    • 25
    • 17
    • 7
    • 2
    • 1
    • 1
    • 1
    ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    免疫原
    Synthesized peptide derived from Human sodium channel.
    亚型
    IgG
    Top Product
    Discover our top product SCN5A Primary Antibody
  • 应用备注
    WB:1:500-1:3000, IHC:1:50-1:100,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    SCN5A (Sodium Channel, Voltage-Gated, Type V, alpha Subunit (SCN5A))
    别名
    SCN5A (SCN5A 产品)
    别名
    Nav1.5 antibody, Nav1.5c antibody, SkM1 antibody, SkM2 antibody, mH1 antibody, CDCD2 antibody, CMD1E antibody, CMPD2 antibody, HB1 antibody, HB2 antibody, HBBD antibody, HH1 antibody, ICCD antibody, IVF antibody, LQT3 antibody, PFHB1 antibody, SSS1 antibody, VF1 antibody, SCAL antibody, sodium voltage-gated channel alpha subunit 5 antibody, sodium channel, voltage-gated, type V, alpha antibody, SCN5A antibody, Scn5a antibody
    背景

    Background: This protein mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na+ ions may pass in accordance with their electrochemical gradient. It is a tetrodotoxin-resistant Na+ channel isoform. This channel is responsible for the initial upstroke of the action potential. Channel inactivation is regulated by intracellular calcium levels.

    Sebastian K.G. Maier, Circulation, Mar 2004, 109: 1421 - 1427.
    T.R. Cummins, Neurology, Jan 2003, 60: 224 - 229.
    Christopher A. Ahern, Circ. Res., May 2005, 96: 991 - 998.
    Jyoti Dhar Malhotra, Circulation, Mar 2001, 103: 1303 - 1310.

    Aliases: Cardiac tetrodotoxin insensitive voltage dependent sodium channel alpha subunit antibody, CDCD2 antibody, CMD1E antibody, CMPD2 antibody, HB1 antibody, HB2 antibody, HBBD antibody, HH1 antibody, ICCD antibody, IVF antibody, LQT3 antibody, PFHB1 antibody, Scn5a (gene name) antibody, Scn5a antibody, SCN5A_HUMAN antibody, Sodium channel protein cardiac muscle alpha subunit antibody, Sodium channel protein cardiac muscle subunit alpha antibody, Sodium channel protein type 5 subunit alpha antibody, Sodium channel protein type V alpha subunit antibody, Sodium channel protein type V subunit alpha antibody, SSS1 antibody, VF1 antibody, Voltage gated sodium channel alpha subunit Nav1.5 antibody, Voltage-gated sodium channel subunit alpha Nav1.5 antibody

    UniProt
    Q14524
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