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- 抗原 See all NFKB2 抗体
- NFKB2 (Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 2 (NFKB2))
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抗原表位
- N-Term
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适用
- 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This NFKB2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 纯化方法
- Antigen affinity
- 免疫原
- An amino acid sequence from the N-terminus of mouse NFKB2 (YDPGLDGIPEYDDFEFS) was used as the immunogen for this NFKB2 (100% rat homology).
- 亚型
- IgG
- Top Product
- Discover our top product NFKB2 Primary Antibody
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anti-Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 2 (NFKB2) (AA 690-899) antibody
NFKB2 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 2 (NFKB2) (AA 1-340) antibodyNFKB2 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 2 (NFKB2) (C-Term) antibodyNFKB2 适用: 人, 大鼠, Cow, Pig, 兔, 马 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 2 (NFKB2) (pSer870) antibodyNFKB2 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 2 (NFKB2) antibodyNFKB2 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 2 (NFKB2) (pSer866) antibodyNFKB2 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 2 (NFKB2) (C-Term) antibodyNFKB2 适用: 人, 小鼠 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 2 (NFKB2) (AA 712-900) antibodyNFKB2 适用: 人, 小鼠 WB, IHC, ELISA, ICC, FACS, Neut 宿主: 小鼠 Monoclonal 5E6A12 unconjugated
anti-Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 2 (NFKB2) (AA 712-900) antibodyNFKB2 适用: 人 WB, IHC, ELISA, ICC, FACS, Neut 宿主: 小鼠 Monoclonal 2F10A7 unconjugated
anti-Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 2 (NFKB2) (AA 151-250) antibodyNFKB2 适用: 人, 小鼠 ELISA, IHC (p), ICC, FACS, IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- The stated application concentrations are suggested starting amounts. Titration of the NFKB2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL
- 限制
- 仅限研究用
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- 缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
- 储存条件
- -20 °C
- 储存方法
- After reconstitution, the NFKB2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- 抗原
- NFKB2 (Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 2 (NFKB2))
- 别名
- NFKB2 (NFKB2 产品)
- 别名
- NF-kappaB2 antibody, lyt antibody, p49 antibody, p49/p100 antibody, p50B antibody, p52 antibody, nuclear factor of kappa light polypeptide gene enhancer in B cells 2, p49/p100 antibody, Nfkb2 antibody
- 背景
- Nuclear Factor Kappa-B, Subunit 2, also known as NFKB or p52/p100 subunit, is a protein that in humans is encoded by the NFKB2 gene. Liptay et al.(1992) mapped the gene for what they called the p49/p100 subunit of NFKB to chromosome 10 by Southern blot analysis of panels of human/Chinese hamster cell hybrids. By fluorescence in situ hybridization(FISH), they confirmed the localization and mapped the gene with greater resolution to 10q24. NFKB2 appears to be the same as LYT10. Claudio et al.(2002) showed that bone marrow(BM) cells from Nfkb2-deficient mice, but not Nfkb1-deficient mice, failed to increase relative and total IgD-positive transitional-1(T1) stage B cells in response to Baff. In vivo, however, Nfkb2-deficient mice did generate mature B cells, but at reduced numbers. Mice of the aly/aly strain, which are naturally deficient in Nik, and mice of the A/WySNJ strain, which have a mutation in Baffr, also failed to produce T1 B cells in response to Baff. Baff stimulation enhanced expression of Bcl2 in T1 B cells, thereby promoting B-cell survival, and caused the processing of the p100 form of the protein to p52, which again required Baffr and Nik, but not Nemo(IKKG). Immunoblot analysis showed that BM cells contained primarily p100.
- UniProt
- Q9WTK5
- 途径
- Toll-Like Receptors Cascades
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