NFKB2 抗体 (AA 690-899)
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北京 101111
Quick Overview for NFKB2 抗体 (AA 690-899) (ABIN3017388)
抗原
See all NFKB2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 690-899
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序列
- AGADIHAENE EPLCPLPSPP TSDSDSDSEG PEKDTRSSFR GHTPLDLTCS TKVKTLLLNA AQNTMEPPLT PPSPAGPGLS LGDTALQNLE QLLDGPEAQG SWAELAERLG LRSLVDTYRQ TTSPSGSLLR SYELAGGDLA GLLEALSDMG LEEGVRLLRG PETRDKLPST EVKEDSAYGS QSVEQEAEKL GPPPEPPGGL CHGHPQPQVH
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 690-899 of human NF-kappaB2 (NP_002493.3).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
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限制
- 仅限研究用
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- NFKB2 (Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 2 (NFKB2))
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别名
- NFKB2
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背景
- This gene encodes a subunit of the transcription factor complex nuclear factor-kappa-B (NFkB). The NFkB complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. The protein encoded by this gene can function as both a transcriptional activator or repressor depending on its dimerization partner. The p100 full-length protein is co-translationally processed into a p52 active form. Chromosomal rearrangements and translocations of this locus have been observed in B cell lymphomas, some of which may result in the formation of fusion proteins. There is a pseudogene for this gene on chromosome 18. Alternative splicing results in multiple transcript variants.,CVID10,H2TF1,LYT-10,LYT10,NF-kB2,p100,p49/p100,p52,Epigenetics & Nuclear Signaling,Transcription Factors,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Inhibition of Apoptosis,Death Receptor Signaling Pathway,Immunology & Inflammation,B Cell Receptor Signaling Pathway,T Cell Receptor Signaling Pathway,IL-6 Receptor Signaling Pathway,NF-kB Signaling Pathway,NFKB2
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分子量
- 47 kDa/96 kDa
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基因ID
- 4791
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UniProt
- Q00653
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途径
- Toll-Like Receptors Cascades
抗原
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