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NFKB2 抗体 (AA 1-340)

NFKB2 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3043293
发货至: 中国
  • 抗原 See all NFKB2 抗体
    NFKB2 (Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 2 (NFKB2))
    抗原表位
    • 16
    • 14
    • 13
    • 13
    • 11
    • 11
    • 6
    • 5
    • 4
    • 4
    • 3
    • 2
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    • 1
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    • 1
    • 1
    • 1
    • 1
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    • 1
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    AA 1-340
    适用
    • 134
    • 95
    • 59
    • 9
    • 8
    • 6
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 133
    • 7
    克隆类型
    • 123
    • 16
    • 1
    多克隆
    标记
    • 78
    • 12
    • 6
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 3
    • 2
    • 1
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    • 1
    • 1
    • 1
    This NFKB2 antibody is un-conjugated
    应用范围
    • 85
    • 48
    • 40
    • 28
    • 22
    • 16
    • 16
    • 13
    • 13
    • 11
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    原理
    Rabbit IgG polyclonal antibody for Nuclear factor NF-kappa-B p100 subunit(NFKB2) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
    交叉反应 (详细)
    No cross reactivity with other proteins.
    产品特性
    Rabbit IgG polyclonal antibody for Nuclear factor NF-kappa-B p100 subunit(NFKB2) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
    Gene Name: nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
    Protein Name: Nuclear factor NF-kappa-B p100 subunit
    纯化方法
    Immunogen affinity purified.
    免疫原
    E.coli-derived human NFkB p100/p52 recombinant protein (Position: M1-R340). Human NFkB p100/p52 shares 96% amino acid (aa) sequence identity with mouse NFkB p100/p52.
    亚型
    IgG
    Top Product
    Discover our top product NFKB2 Primary Antibody
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, The detection limit for NFkB p100/p52 is approximately 0.25 ng/lane under reducing conditions.
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • Sun, Xue, Xue, Ren, Wu, Wang: "Acetylpuerarin protects against OGD-induced cell injury in BV2 microglia by inhibiting HMGB1 release." in: Die Pharmazie, Vol. 73, Issue 2, pp. 92-97, (2018) (PubMed).

    Yu, Wang, He, Wang, Gao, Ren, Shi et al.: "Curcumin exerts anti-inflammatory and antioxidative properties in 1-methyl-4-phenylpyridinium ion (MPP(+))-stimulated mesencephalic astrocytes by interference with TLR4 and downstream signaling ..." in: Cell stress & chaperones, Vol. 21, Issue 4, pp. 697-705, (2017) (PubMed).

    Kan, Zhou, Jin, Yang: "Effects of PDTC on NF-?B expression and apoptosis in rats with severe acute pancreatitis-associated lung injury." in: International journal of clinical and experimental medicine, Vol. 8, Issue 3, pp. 3258-70, (2015) (PubMed).

    Wang, Wang, Fang, Zhou, Liu, Su: "High glucose induces and activates Toll-like receptor 4 in endothelial cells of diabetic retinopathy." in: Diabetology & metabolic syndrome, Vol. 7, pp. 89, (2015) (PubMed).

    Yang, Wang, Wang, Xu, He, Wen, Yan, Su, Zhu: "Toll-like receptor 4 prompts human breast cancer cells invasiveness via lipopolysaccharide stimulation and is overexpressed in patients with lymph node metastasis." in: PLoS ONE, Vol. 9, Issue 10, pp. e109980, (2014) (PubMed).

    Zhao, Wang, Liu, Sun, Kazuhiro: "Protective effects of glutamine in a rat model of endotoxemia." in: Molecular medicine reports, Vol. 6, Issue 4, pp. 739-44, (2012) (PubMed).

    Li, Chen, Zhang, Zhu, Liu, Liang, Sun, Liao, Gong: "Protective effect of glutamine-enriched early enteral nutrition on intestinal mucosal barrier injury after liver transplantation in rats." in: American journal of surgery, Vol. 199, Issue 1, pp. 35-42, (2010) (PubMed).

  • 抗原
    NFKB2 (Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 2 (NFKB2))
    别名
    NFKB2 (NFKB2 产品)
    别名
    NF-kappaB2 antibody, lyt antibody, p49 antibody, p49/p100 antibody, p50B antibody, p52 antibody, nuclear factor of kappa light polypeptide gene enhancer in B cells 2, p49/p100 antibody, Nfkb2 antibody
    背景
    NFKB2, also known as nuclear factor NF-kappa-B p100 subunit, is a protein that in humans is encoded by the NFKB2 gene. It is mapped to 10q24.32. This gene encodes a subunit of the transcription factor complex nuclear factor-kappa-B (NFKB). NFKB is activated by a wide variety of stimuli such as cytokines, oxidant-free radicals, inhaled particles, ultraviolet irradiation, and bacterial or viral products. The NFkB complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. The protein encoded by this gene can function as both a transcriptional activator or repressor depending on its dimerization partner.

    Synonyms: DNA binding factor KBF2 antibody|DNA-binding factor KBF2 antibody|H2TF1 antibody|Lymphocyte translocation chromosome 10 antibody|Lymphocyte translocation chromosome 10 protein antibody|Lyt 10 antibody|Lyt10 antibody|NF kB2 antibody|NFKB2 antibody|NFKB2_HUMAN antibody|Nuclear factor NF kappa B p100 subunit antibody|Nuclear factor NF kappa B p52 subunit antibody|Nuclear factor NF-kappa-B p52 subunit antibody|Nuclear factor of kappa light chain gene enhancer in B cells 2 antibody|Nuclear factor of kappa light polypeptide gene enhancer in B cells 2 antibody|Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 antibody|Oncogene Lyt 10 antibody|Oncogene Lyt-10 antibody|p105 antibody|p49/p100 antibody
    基因ID
    4791
    UniProt
    Q00653
    途径
    Toll-Like Receptors Cascades
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