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DDR1 抗体 (C-Term)

DDR1 适用: 人, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3030733
发货至: 中国
  • 抗原 See all DDR1 抗体
    DDR1 (Discoidin Domain Receptor tyrosine Kinase 1 (DDR1))
    抗原表位
    • 20
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    C-Term
    适用
    • 87
    • 43
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    • 5
    • 3
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    • 2
    • 2
    人, 大鼠
    宿主
    • 94
    • 8
    克隆类型
    • 93
    • 8
    • 1
    多克隆
    标记
    • 49
    • 6
    • 4
    • 4
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    This DDR1 antibody is un-conjugated
    应用范围
    • 81
    • 42
    • 26
    • 26
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    • 13
    • 10
    • 6
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    • 5
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    Western Blotting (WB)
    纯化方法
    Antigen affinity
    免疫原
    An amino acid sequence from the C-terminus of human DDR1/RKT6 (FSQLHRFLAEDALNTV) was used as the immunogen for this DDR1 antibody.
    亚型
    IgG
    Top Product
    Discover our top product DDR1 Primary Antibody
  • 应用备注
    The stated application concentrations are suggested starting amounts. Titration of the DDR1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL
    限制
    仅限研究用
  • 缓冲液
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    储存条件
    -20 °C
    储存方法
    After reconstitution, the DDR1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原
    DDR1 (Discoidin Domain Receptor tyrosine Kinase 1 (DDR1))
    别名
    DDR1 (DDR1 产品)
    别名
    CG11573 antibody, CG13984 antibody, CG13985 antibody, CG33531 antibody, CG9488 antibody, CG9490 antibody, CT33540 antibody, DDR antibody, Dmel\\CG33531 antibody, Dmel_CG13984 antibody, 6030432F18 antibody, AI323681 antibody, CD167a antibody, Cak antibody, Nep antibody, PTK3A antibody, CAK antibody, CD167 antibody, EDDR1 antibody, HGK2 antibody, MCK10 antibody, NEP antibody, NTRK4 antibody, PTK3 antibody, RTK6 antibody, TRKE antibody, Drd1 antibody, PTK3D antibody, Discoidin domain receptor antibody, discoidin domain receptor family, member 1 antibody, discoidin domain receptor tyrosine kinase 1 antibody, Ddr antibody, Ddr1 antibody, DDR1 antibody
    背景
    Discoidin domain receptor family, member 1, also known as NEP, EDDR1, NTRK4, TRKE, DDR, CAK or RTK6, is a human gene. The protein encoded by this gene is a DDR that is widely expressed in normal and transformed epithelial cells and is activated by various types of collagen. This protein belongs to a subfamily of tyrosine kinase receptors with a homology region to the Dictyostelium discoideum protein discoidin I in their extracellular domain. The fibrillar collagens and immobilized collagen activated DDR1 receptor phosphorylation after prolonged treatment. Bhatt et al.(2000) showed that the protein was highly expressed in the cerebellum of developing and adult mouse brain, and that both DDR1 and Collagen IV were highly expressed in the pial layer of the cerebellar cortex. Cocultures of Collagen I- and IV-expressing mouse pial cells with DDR1-expressing granule cells resulted in granule cell neurite extension. Inhibition of collagen-DDR1 signaling reduced granule cell neurite elongation.
    UniProt
    Q08345
    途径
    RTK signaling, Smooth Muscle Cell Migration
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