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TICAM1 抗体

TICAM1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN302873
发货至: 中国
  • 抗原 See all TICAM1 抗体
    TICAM1 (Toll-Like Receptor Adaptor Molecule 1 (TICAM1))
    适用
    • 27
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    宿主
    • 25
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    克隆类型
    • 27
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    多克隆
    标记
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    This TICAM1 antibody is un-conjugated
    应用范围
    • 23
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    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    This antibody reacts to a peptide corresponding to 14 amino acids near the C-terminus of TRIF.
    纯化方法
    Ion exchange chromatography
    免疫原
    Synthetic peptide
    Top Product
    Discover our top product TICAM1 Primary Antibody
  • 应用备注
    Western Blot: 2 - 4 μg/mL. Immunohistochemistry: 5 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 缓冲液
    Phosphate buffered saline, containing 0.02 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C to -70 °C for longer.
  • 抗原
    TICAM1 (Toll-Like Receptor Adaptor Molecule 1 (TICAM1))
    别名
    TICAM1 / TRIF (TICAM1 产品)
    别名
    IIAE6 antibody, MyD88-3 antibody, PRVTIRB antibody, TICAM-1 antibody, TRIF antibody, AW046014 antibody, AW547018 antibody, trif antibody, toll like receptor adaptor molecule 1 antibody, toll-like receptor adaptor molecule 1 antibody, TICAM1 antibody, Ticam1 antibody, ticam1 antibody
    背景
    TRIF is a member of the Toll/interleukin-1 receptor (TIR) family, a group of proteins that include the Toll-like receptors (TLRs). TLRs are signaling molecules that recognize different pathogen-associated molecular patterns (PAMPs) and serve as an important link between the innate and adaptive immune responses. TRIF, along with other molecules such as TIRP, TIRAP, and MyD88, serves as an adaptor protein to several of the TLR molecules. Following activation of TLR3 and TLR4, TRIF engages the kinase TBK1 and allows its subsequent activation of the interferon regulatory factor (IRF)-3. TRIF is also involved in the activation of TNF receptor associated factor (TRAF)-6, and ultimately the activation of NF-kB.Synonyms: PRVTIRB, Proline-rich vinculin and TIR domain-containing protein B, Putative NF-kappa-B-activating protein 502H, TICAM-1, TIR domain-containing adapter molecule 1, Toll-interleukin 1 receptor domain-containing adapter protein inducing interferon-beta
    基因ID
    148022
    NCBI登录号
    NP_891549
    UniProt
    Q8IUC6
    途径
    TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Toll-Like Receptors Cascades
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