TICAM1 产品
(Toll-Like Receptor Adaptor Molecule 1 (TICAM1))
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This gene encodes an adaptor protein containing a Toll/interleukin-1 receptor (TIR) homology domain, which is an intracellular signaling domain that mediates protein-protein interactions between the Toll-like receptors (TLRs) and signal-transduction components. This protein is involved in native immunity against invading pathogens. It specifically interacts with toll-like receptor 3, but not with other TLRs, and this association mediates dsRNA induction of interferon-beta through activation of nuclear factor kappa-B, during an antiviral immune response. [provided by RefSeq, Jan 2012].
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Featured TICAM1 Categories
TICAM1 抗体
High quality antibodies with extensive validation data.
TICAM1 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
TICAM1 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended TICAM1 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (7)
Cat. No.
ABIN7441424
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (5)
Cat. No.
ABIN7189088
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Mouse
Application
WB, IHC, IP, ICC
Validations
- (5)
Cat. No.
ABIN7441427
Quantity
100 μL
Datasheet
Datasheet
Recommended TICAM1 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6960044
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6960045
Quantity
96 tests
Datasheet
Datasheet
Recommended TICAM1 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7125415
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1322755
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
Cat. No.
ABIN3095801
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our TICAM1 Products
: "TLR4-Mediated Pathway Triggers Interferon-Independent G0 Arrest and Antiviral SAMHD1 Activity in Macrophages." in: Cell reports, Vol. 30, Issue 12, pp. 3972-3980.e5, (2020) (PubMed).: "SjHSP60 induces CD4+ CD25+ Foxp3+ Tregs via TLR4-Mal-drived production of TGF-β in macrophages." in: Immunology and cell biology, Vol. 96, Issue 9, pp. 958-968, (2019) (PubMed).
: "Atractylodes macrocephala polysaccharides regulate the innate immunity of colorectal cancer cells by modulating the TLR4 signaling pathway." in: OncoTargets and therapy, Vol. 12, pp. 7111-7121, (2019) (PubMed).
: "Inositol polyphosphate multikinase promotes Toll-like receptor-induced inflammation by stabilizing TRAF6." in: Science advances, Vol. 3, Issue 4, pp. e1602296, (2017) (PubMed).
: "Biphalin, a Dimeric Enkephalin, Alleviates LPS-Induced Activation in Rat Primary Microglial Cultures in Opioid Receptor-Dependent and Receptor-Independent Manners." in: Neural plasticity, Vol. 2017, pp. 3829472, (2017) (PubMed).
: "Curcumin exerts anti-inflammatory and antioxidative properties in 1-methyl-4-phenylpyridinium ion (MPP(+))-stimulated mesencephalic astrocytes by interference with TLR4 and downstream signaling ..." in: Cell stress & chaperones, Vol. 21, Issue 4, pp. 697-705, (2017) (PubMed).
: "Toll-Like Receptor 4 Mediates Methamphetamine-Induced Neuroinflammation through Caspase-11 Signaling Pathway in Astrocytes." in: Frontiers in molecular neuroscience, Vol. 10, pp. 409, (2017) (PubMed).
: "Interferon β (IFN-β) Production during the Double-stranded RNA (dsRNA) Response in Hepatocytes Involves Coordinated and Feedforward Signaling through Toll-like Receptor 3 (TLR3), RNA-dependent ..." in: The Journal of biological chemistry, Vol. 291, Issue 29, pp. 15093-107, (2016) (PubMed).
: "Synergy of TLR3 and 7 ligands significantly enhances function of DCs to present inactivated PRRSV antigen through TRIF/MyD88-NF-κB signaling pathway." in: Scientific reports, Vol. 6, pp. 23977, (2016) (PubMed).
: "Pinocembrin protects hemorrhagic brain primarily by inhibiting toll-like receptor 4 and reducing M1 phenotype microglia." in: Brain, behavior, and immunity, Vol. 61, pp. 326-339, (2016) (PubMed).
Synonyms and alternative names related to TICAM1
toll like receptor adaptor molecule 1 (TICAM1), toll-like receptor adaptor molecule 1 (Ticam1), toll-like receptor adaptor molecule 1 (ticam1), AW046014, AW547018, IIAE6, MyD88-3, PRVTIRB, TICAM-1, TRIF, trifProtein level used designations for TICAM1
- TIR domain containing adaptor inducing interferon-beta
- TIR domain-containing adapter molecule 1
- TIR domain-containing adapter protein inducing IFN-beta
- proline-rich, vinculin and TIR domain-containing protein B
- putative NF-kappa-B-activating protein 502H
- toll-interleukin-1 receptor domain-containing adapter protein inducing interferon beta
- toll-interleukin I receptor domain containing adaptor molecule 1
- toll-like receptor adaptor molecule 1
- TIR domain-containing adapter molecule 1-like
- TIR domain-containing adaptor inducing interferon-beta
- toll-interleukin 1 receptor domain-containing adapter protein inducing interferon-beta
- TICAM-1
- TIR-domain containing adaptor inducing IFN-beta
- TRIF/TICAM1
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