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TIGIT 产品

(T Cell Immunoreceptor with Ig and ITIM Domains (TIGIT))

Categories

This gene encodes a member of the PVR (poliovirus receptor) family of immunoglobin proteins. The product of this gene is expressed on several classes of T cells including follicular B helper T cells (TFH). The protein has been shown to bind PVR with high affinity\; this binding is thought to assist interactions between TFH and dendritic cells to regulate T cell dependent B cell responses.[provided by RefSeq, Sep 2009].

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Featured TIGIT Categories

TIGIT 抗体

High quality antibodies with extensive validation data.

TIGIT ELISA试剂盒

Reliable ELISA kits for a wide range of species.

TIGIT 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended TIGIT 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, ICC, IP
Validations
  • (5)
Cat. No. ABIN7439486
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC, FACS, Coat, StM
Validations
  • (4)
Cat. No. ABIN6939305
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, ICC, FACS, Neut
Validations
  • (4)
Cat. No. ABIN7193227
Quantity 0.1 mg
Datasheet Datasheet

Recommended TIGIT ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6959836
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6730832
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN4884793
Quantity 96 tests
Datasheet Datasheet

Recommended TIGIT 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (6)
Cat. No. ABIN7275729
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (6)
Cat. No. ABIN7275728
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (4)
Cat. No. ABIN7275730
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our TIGIT Products

Bai, Gao, Hu, Liu, Li, Dong, Huang, Zhu, Zhou, Li, Shao: "Self-Assembled Multivalent Aptamer Nanoparticles with Potential CAR-like Characteristics Could Activate T Cells and Inhibit Melanoma Growth." in: Molecular therapy oncolytics, Vol. 17, pp. 9-20, (2020) (PubMed).

Brockmann, Soukou, Steglich, Czarnewski, Zhao, Wende, Bedke, Ergen, Manthey, Agalioti, Geffken, Seiz, Parigi, Sorini, Geginat, Fujio, Jacobs, Roesch, Izbicki, Lohse, Flavell, Krebs, Gustafsson et al.: "Molecular and functional heterogeneity of IL-10-producing CD4+ T cells. ..." in: Nature communications, Vol. 9, Issue 1, pp. 5457, (2019) (PubMed).

Nuñez, Ziblat, Secchiari, Torres, Sierra, Raffo Iraolagoitia, Araya, Domaica, Fuertes, Zwirner: "Human M2 Macrophages Limit NK Cell Effector Functions through Secretion of TGF-β and Engagement of CD85j." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 200, Issue 3, pp. 1008-1015, (2018) (PubMed).

Downs-Canner, Berkey, Delgoffe, Edwards, Curiel, Odunsi, Bartlett, Obermajer: "Suppressive IL-17A+Foxp3+and ex-Th17 IL-17AnegFoxp3+Tregcells are a source of tumour-associated Tregcells." in: Nature communications, Vol. 8, pp. 14649, (2017) (PubMed).

Yasuma, Yasunaga, Takemoto, Sugata, Mitobe, Takenouchi, Nakagawa, Suzuki, Matsuoka: "HTLV-1 bZIP Factor Impairs Anti-viral Immunity by Inducing Co-inhibitory Molecule, T Cell Immunoglobulin and ITIM Domain (TIGIT)." in: PLoS pathogens, Vol. 12, Issue 1, pp. e1005372, (2016) (PubMed).

Gur, Ibrahim, Isaacson, Yamin, Abed, Gamliel, Enk, Bar-On, Stanietsky-Kaynan, Coppenhagen-Glazer, Shussman, Almogy, Cuapio, Hofer, Mevorach, Tabib, Ortenberg, Markel, Miklić, Jonjic, Brennan, Garrett et al.: "Binding of the Fap2 protein of Fusobacterium nucleatum to human inhibitory receptor TIGIT protects tumors from immune cell attack. ..." in: Immunity, Vol. 42, Issue 2, pp. 344-55, (2015) (PubMed).

Zhang, Wang, Zhou, Liang, Bai, Yang, Gu, Gao, Dong, Zhu, Chen: "Increased expression of TIGIT on CD4+ T cells ameliorates immune-mediated bone marrow failure of aplastic anemia." in: Journal of cellular biochemistry, Vol. 115, Issue 11, pp. 1918-27, (2014) (PubMed).

Stanietsky, Rovis, Glasner, Seidel, Tsukerman, Yamin, Enk, Jonjic, Mandelboim: "Mouse TIGIT inhibits NK-cell cytotoxicity upon interaction with PVR." in: European journal of immunology, Vol. 43, Issue 8, pp. 2138-50, (2013) (PubMed).

Synonyms and alternative names related to TIGIT

T-cell immunoreceptor with Ig and ITIM domains (TIGIT), T cell immunoreceptor with Ig and ITIM domains (Tigit), ENSMUSG00000071552, RGD1563191, VSIG9, VSTM3, Vstm3, WUCAM

Protein level used designations for TIGIT

  • T-cell immunoreceptor with Ig and ITIM domains
  • V-set and immunoglobulin domain containing 9
  • V-set and immunoglobulin domain-containing protein 9
  • V-set and transmembrane domain containing 3
  • V-set and transmembrane domain-containing protein 3
  • Washington University cell adhesion molecule
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