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TICAM1 抗体 (Internal Region)

TICAM1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6265566
发货至: 中国
  • 抗原 See all TICAM1 抗体
    TICAM1 (Toll-Like Receptor Adaptor Molecule 1 (TICAM1))
    抗原表位
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    适用
    • 26
    • 9
    • 2
    • 2
    人, 小鼠, 大鼠
    宿主
    • 24
    • 3
    • 3
    克隆类型
    • 26
    • 4
    多克隆
    标记
    • 23
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TICAM1 antibody is un-conjugated
    应用范围
    • 22
    • 6
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
    特异性
    TICAM1 Antibody detects endogenous levels of total TICAM1.
    预测反应
    Pig,Zebrafish,Bovine,Horse,Sheep,Dog,Chicken
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human TICAM1, corresponding to a region within the internal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product TICAM1 Primary Antibody
  • 应用备注
    WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    TICAM1 (Toll-Like Receptor Adaptor Molecule 1 (TICAM1))
    别名
    TICAM1 (TICAM1 产品)
    别名
    IIAE6 antibody, MyD88-3 antibody, PRVTIRB antibody, TICAM-1 antibody, TRIF antibody, AW046014 antibody, AW547018 antibody, trif antibody, toll like receptor adaptor molecule 1 antibody, toll-like receptor adaptor molecule 1 antibody, TICAM1 antibody, Ticam1 antibody, ticam1 antibody
    背景

    Description: Involved in innate immunity against invading pathogens. Adapter used by TLR3 and TLR4 (through TICAM2) to mediate NF-kappa-B and interferon-regulatory factor (IRF) activation, and to induce apoptosis. Ligand binding to these receptors results in TRIF recruitment through its TIR domain. Distinct protein-interaction motifs allow recruitment of the effector proteins TBK1, TRAF6 and RIPK1, which in turn, lead to the activation of transcription factors IRF3 and IRF7, NF-kappa-B and FADD respectively.

    Gene: TICAM1

    分子量
    76kDa
    基因ID
    148022
    UniProt
    Q8IUC6
    途径
    TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Toll-Like Receptors Cascades
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