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EGFR 抗体

EGFR 适用: 人 FACS, IP, InhA 宿主: 小鼠 Monoclonal B1D8 unconjugated
产品编号 ABIN3026442
发货至: 中国
  • 抗原 See all EGFR 抗体
    EGFR (Epidermal Growth Factor Receptor (EGFR))
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    小鼠
    克隆类型
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    单克隆
    标记
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    This EGFR antibody is un-conjugated
    应用范围
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    Flow Cytometry (FACS), Immunoprecipitation (IP), Inhibition Assay (InhA)
    无交叉反应
    小鼠, 大鼠
    产品特性
    This antibody reacts with the extracellular domain of EGF receptor and blocks the EGF/TGFa induced activation. It also blocks tumor growth in vivo. It is excellent for purification of EGF receptor. < a href=../search_result.php?search_txt=egfr>EGFR is type I receptor tyrosine kinase with sequence homology to < a href=../search_result.php?search_txt=erbb2>ErbB2, -3 -4 or < a href=../search_result.php?search_txt=her2>HER2, -3 -4. It binds to Epidermal Growth Factor (EGF), < a href=../search_result.php?search_txt=TGFa>Transforming Growth Factor-a (TGFa), Heparin-binding EGF (HB-EGF), amphiregulin, betacellulin and epiregulin.
    纯化方法
    Protein G purified monoclonal antibody
    免疫原
    Microsomes from A431 cells were used as the immunogen for this antibody.
    克隆位点
    B1D8
    亚型
    IgG2a kappa
    Top Product
    Discover our top product EGFR Primary Antibody
  • 应用备注
    The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the antibody to be titered up or down for optimal performance.\. Functional Activity (Inhibition): antibody blocks EGF receptor activation, inhibits A431 cell proliferation, arrests tumor growth in vivo, affinity purification,IP: 1-2 μg/500 μg protein lysate,FACS: 0.5-1 μg/million cells
    限制
    仅限研究用
  • 浓度
    0.2 mg/mL
    缓冲液
    0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store the EGF Receptor antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
  • 抗原
    EGFR (Epidermal Growth Factor Receptor (EGFR))
    别名
    EGF Receptor (EGFR 产品)
    别名
    C-erb antibody, CG10079 antibody, D-EGFR antibody, D-Egf antibody, DEGFR antibody, DER antibody, DER flb antibody, DER/EGFR antibody, DER/faint little ball antibody, DER/top antibody, DER/torpedo antibody, DER1 antibody, DEgfr antibody, Degfr antibody, Der antibody, DmHD-33 antibody, Dmel\\CG10079 antibody, EFG-R antibody, EGF-R antibody, EGFR antibody, EGFr antibody, EGfr antibody, EK2-6 antibody, Egf antibody, Egf-r antibody, EgfR antibody, El antibody, Elp antibody, Elp-1 antibody, Elp-B1 antibody, Elp-B1RB1 antibody, HD-33 antibody, TOP antibody, Torpedo/DER antibody, Torpedo/Egfr antibody, c-erbB antibody, d-egf-r antibody, dEGFR antibody, dEGFR1 antibody, dEgfr antibody, der antibody, egfr antibody, flb antibody, l(2)05351 antibody, l(2)09261 antibody, l(2)57DEFa antibody, l(2)57EFa antibody, l(2)57Ea antibody, mor1 antibody, top antibody, top/DER antibody, top/flb antibody, torpedo/Egfr antibody, torpedo/egfr antibody, EGFR12 antibody, EGFR15 antibody, egfr1 antibody, Erbb2 antibody, ERBB antibody, ERBB1 antibody, HER1 antibody, PIG61 antibody, mENA antibody, ErbB-1 antibody, Errp antibody, 9030024J15Rik antibody, AI552599 antibody, Erbb antibody, Errb1 antibody, Wa5 antibody, wa-2 antibody, wa2 antibody, epidermal growth factor receptor antibody, Epidermal growth factor receptor antibody, epidermal growth factor receptor a (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian) antibody, EGFR antibody, Egfr antibody, egfra antibody, egfr1 antibody, LOC5564544 antibody
    背景
    This antibody reacts with the extracellular domain of EGF receptor and blocks the EGF/TGFa induced activation. It also blocks tumor growth in vivo. It is excellent for purification of EGF receptor. < a href=../search_result.php?search_txt=egfr>EGFR is type I receptor tyrosine kinase with sequence homology to < a href=../search_result.php?search_txt=erbb2>ErbB2, -3 -4 or < a href=../search_result.php?search_txt=her2>HER2, -3 -4. It binds to Epidermal Growth Factor (EGF), < a href=../search_result.php?search_txt=TGFa>Transforming Growth Factor-a (TGFa), Heparin-binding EGF (HB-EGF), amphiregulin, betacellulin and epiregulin.
    基因ID
    1956
    途径
    NF-kappaB Signaling, RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Stem Cell Maintenance, Hepatitis C, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, EGFR Downregulation, S100 Proteins
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