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RPA2 抗体 (AA 80-270)

RPA2 适用: 人 WB, IHC, IP 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3023166
发货至: 中国
  • 抗原 See all RPA2 抗体
    RPA2 (Replication Protein A2, 32kDa (RPA2))
    抗原表位
    • 37
    • 15
    • 8
    • 5
    • 5
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 80-270
    适用
    • 87
    • 68
    • 43
    • 4
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    宿主
    • 103
    • 15
    • 2
    • 1
    克隆类型
    • 94
    • 27
    多克隆
    标记
    • 72
    • 6
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    This RPA2 antibody is un-conjugated
    应用范围
    • 99
    • 35
    • 32
    • 28
    • 26
    • 24
    • 23
    • 18
    • 10
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)
    序列
    IRHAEKAPTN IVYKIDDMTA APMDVRQWVD TDDTSSENTV VPPETYVKVA GHLRSFQNKK SLVAFKIMPL EDMNEFTTHI LEVINAHMVL SKANSQPSAG RAPISNPGMS EAGNFGGNSF MPANGLTVAQ NQVLNLIKAC PRPEGLNFQD LKNQLKHMSV SSIKQAVDFL SNEGHIYSTV DDDHFKSTDA E
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Polyclonal Antibodies
    免疫原
    Recombinant fusion protein containing a sequence corresponding to amino acids 80-270 of human RPA2 (NP_002937.1).
    亚型
    IgG
    Top Product
    Discover our top product RPA2 Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IP,1:50 - 1:200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid freeze / thaw cycles
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    RPA2 (Replication Protein A2, 32kDa (RPA2))
    别名
    RPA2 (RPA2 产品)
    别名
    REPA2 antibody, RPA32 antibody, 153194_at antibody, CG9273 antibody, Dmel\\CG9273 antibody, dRPA2 antibody, rpa antibody, zgc:109822 antibody, ik:tdsubc_2g1 antibody, xx:tdsubc_2g1 antibody, repa2 antibody, rpa32 antibody, RPA2 antibody, GB13976 antibody, LOC100230445 antibody, AA409079 antibody, AI325195 antibody, AU020965 antibody, RPA34 antibody, Rf-A2 antibody, replication protein A2 antibody, Replication protein A2 antibody, replication protein A2, 32kDa antibody, replication protein A 32 kDa subunit antibody, RPA2 antibody, Rpa2 antibody, rpa2 antibody, LOC725418 antibody, RPA2_2 antibody
    背景
    As part of the heterotrimeric replication protein A complex (RPA/RP-A, binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. In the cellular response to DNA damage, the RPA complex controls DNA repair and DNA damage checkpoint activation. Through recruitment of ATRIP activates the ATR kinase a master regulator of the DNA damage response. It is required for the recruitment of the DNA double-strand break repair factors RAD51 and RAD52 to chromatin in response to DNA damage. Also recruits to sites of DNA damage proteins like XPA and XPG that are involved in nucleotide excision repair and is required for this mechanism of DNA repair. Plays also a role in base excision repair (BER probably through interaction with UNG. Also recruits SMARCAL1/HARP, which is involved in replication fork restart, to sites of DNA damage. May also play a role in telomere maintenance.,REPA2,RP-A p32,RP-A p34,RPA32,RPA2,RP-Ap32,RP-Ap34,Epigenetics & Nuclear Signaling,DNA Damage & Repair,RPA2
    分子量
    29 kDa/30 kDa/38 kDa
    基因ID
    6118
    UniProt
    P15927
    途径
    Telomere Maintenance, DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA
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