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RPA2 产品

(Replication Protein A2, 32kDa (RPA2))

Categories

Required for DNA recombination, repair and replication. The activity of RP-A is mediated by single-stranded DNA binding and protein interactions. Required for the efficient recruitment of the DNA double-strand break repair factor RAD51 to chromatin in response to DNA damage (By similarity). Required for simian virus 40 DNA replication in vitro. It participates in a very early step in initiation.

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Featured RPA2 Categories

RPA2 抗体

High quality antibodies with extensive validation data.

RPA2 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

RPA2 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended RPA2 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IF, IHC (p)
Validations
  • (7)
Cat. No. ABIN519843
Quantity 50 μg
Datasheet Datasheet
Reactivity Human, Monkey
Application WB, IHC, IF, IP, IHC (p), FACS
Validations
  • (21)
Cat. No. ABIN1500733
Quantity 100 μL
Datasheet Datasheet
Reactivity Dog, Human, Monkey, Rat
Application WB, IHC, IF, IP, IHC (p), FACS
Validations
  • (16)
Cat. No. ABIN1500735
Quantity 100 μL
Datasheet Datasheet

Recommended RPA2 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse
Analytical Method Qualitative Cell ELISA
Validations
Cat. No. ABIN1380430
Quantity 2 x 96 tests
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validations
Cat. No. ABIN1380853
Quantity 2 x 96 tests
Datasheet Datasheet

Recommended RPA2 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7124826
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7124827
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1318502
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our RPA2 Products

Warren, Eastman: "Inhibition of checkpoint kinase 1 following gemcitabine-mediated S phase arrest results in CDC7- and CDK2-dependent replication catastrophe." in: The Journal of biological chemistry, Vol. 294, Issue 6, pp. 1763-1778, (2019) (PubMed).

Chlenski, Park, Dobratic, Salwen, Budke, Park, Miller, Applebaum, Wilkinson, Nakamura, Connell, Cohn: "Maternal Embryonic Leucine Zipper Kinase (MELK), a Potential Therapeutic Target for Neuroblastoma." in: Molecular cancer therapeutics, Vol. 18, Issue 3, pp. 507-516, (2019) (PubMed).

Sundaravinayagam, Rahjouei, Andreani, Tupiņa, Balasubramanian, Saha, Delgado-Benito, Coralluzzo, Daumke, Di Virgilio: "53BP1 Supports Immunoglobulin Class Switch Recombination Independently of Its DNA Double-Strand Break End Protection Function." in: Cell reports, Vol. 28, Issue 6, pp. 1389-1399.e6, (2019) (PubMed).

Her, Ray, Altshuler, Zheng, Bunting: "53BP1 Mediates ATR-Chk1 Signaling and Protects Replication Forks under Conditions of Replication Stress." in: Molecular and cellular biology, Vol. 38, Issue 8, (2018) (PubMed).

Tang, Yang, Wang, Zeng, Wang, Wang, Zhao, Guo, Liu, Li, Chen: "Active DNA end processing in micronuclei of ovarian cancer cells." in: BMC cancer, Vol. 18, Issue 1, pp. 426, (2018) (PubMed).

Maya-Mendoza, Moudry, Merchut-Maya, Lee, Strauss, Bartek: "High speed of fork progression induces DNA replication stress and genomic instability." in: Nature, Vol. 559, Issue 7713, pp. 279-284, (2018) (PubMed).

Simonetta, de Krijger, Serrat, Moatti, Fortunato, Hoekman, Bleijerveld, Altelaar, Jacobs: "H4K20me2 distinguishes pre-replicative from post-replicative chromatin to appropriately direct DNA repair pathway choice by 53BP1-RIF1-MAD2L2." in: Cell cycle (Georgetown, Tex.), Vol. 17, Issue 1, pp. 124-136, (2018) (PubMed).

Yu, Huang, Shieh: "Requirement for human Mps1/TTK in oxidative DNA damage repair and cell survival through MDM2 phosphorylation." in: Nucleic acids research, Vol. 44, Issue 3, pp. 1133-50, (2016) (PubMed).

Moudry, Watanabe, Wolanin, Bartkova, Wassing, Watanabe, Strauss, Troelsgaard Pedersen, Oestergaard, Lisby, Andújar-Sánchez, Maya-Mendoza, Esashi, Lukas, Bartek: "TOPBP1 regulates RAD51 phosphorylation and chromatin loading and determines PARP inhibitor sensitivity." in: The Journal of cell biology, Vol. 212, Issue 3, pp. 281-8, (2016) (PubMed).

Hasegawa, Okabe, Okamoto, Nakano, Shin-ya, Seimiya: "G-quadruplex ligand-induced DNA damage response coupled with telomere dysfunction and replication stress in glioma stem cells." in: Biochemical and biophysical research communications, Vol. 471, Issue 1, pp. 75-81, (2016) (PubMed).

Synonyms and alternative names related to RPA2

replication protein A2 (RPA2), Replication protein A2 (RPA2), replication protein A2 (Rpa2), replication protein A2 (rpa2), replication protein A2, 32kDa (RPA2), replication protein A 32 kDa subunit (LOC725418), replication protein A2 (RPA2_2), 153194_at, AA409079, AI325195, AU020965, CG9273, Dmel\\CG9273, dRPA2, GB13976, ik:tdsubc_2g1, LOC100230445, REPA2, repa2, Rf-A2, rpa, RPA2, RPA32, rpa32, RPA34, xx:tdsubc_2g1, zgc:109822

Protein level used designations for RPA2

  • RF-A protein 2
  • RP-A p32
  • RP-A p34
  • replication factor A protein 2
  • replication protein A 32 kDa subunit
  • replication protein A 34 kDa subunit
  • CG9273-PA
  • CG9273-PB
  • RPA2-PA
  • RPA2-PB
  • replication protein A, subunit 2
  • replication protein A2
  • p32-subunit of replication protein A
  • RPA p32
  • replication protein A2, 32kDa
  • GLEAN_05650
  • putative replication protein A middle subunit
  • 30-kDa protein
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