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RPA2 Protein (AA 1-270) (His tag)

RPA2 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 85 % by SDS – PAGE SDS
产品编号 ABIN7279229
发货至: 中国
  • 抗原 See all RPA2 蛋白
    RPA2 (Replication Protein A2, 32kDa (RPA2))
    蛋白类型
    Recombinant
    产品特性
    AA 1-270
    宿主
    • 5
    • 1
    • 1
    • 1
    资源
    • 4
    • 2
    • 1
    • 1
    大肠杆菌(E. Coli)
    标记
    This RPA2 protein is labelled with His tag.
    应用范围
    SDS-PAGE (SDS)
    产品特性
    RPA2, 1-270aa, Human, His tag, E.coli
    纯度
    > 85 % by SDS – PAGE
    Top Product
    Discover our top product RPA2 蛋白
  • 限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.5 mg/ml (determined by Bradford assay)
    缓冲液
    Liquid. In 20mM Tris-HCl buffer(pH 8.0) containing 10% glycerol, 2mM DTT, 0.1M NaCl.
    储存条件
    4 °C
  • 抗原
    RPA2 (Replication Protein A2, 32kDa (RPA2))
    别名
    RPA2 (RPA2 产品)
    别名
    REPA2 Protein, RPA32 Protein, 153194_at Protein, CG9273 Protein, Dmel\\CG9273 Protein, dRPA2 Protein, rpa Protein, zgc:109822 Protein, ik:tdsubc_2g1 Protein, xx:tdsubc_2g1 Protein, repa2 Protein, rpa32 Protein, RPA2 Protein, GB13976 Protein, LOC100230445 Protein, AA409079 Protein, AI325195 Protein, AU020965 Protein, RPA34 Protein, Rf-A2 Protein, replication protein A2 Protein, Replication protein A2 Protein, replication protein A2, 32kDa Protein, replication protein A 32 kDa subunit Protein, RPA2 Protein, Rpa2 Protein, rpa2 Protein, LOC725418 Protein, RPA2_2 Protein
    背景
    Replication Protein A (RPA) is a single stranded DNA binding protein. Human RPA is a heterotrimeric protein containing subunits of 14, 32 and 70kDa. This protein complex is highly conserved in eukaryotes and is essential in DNA replication, homologous recombination and nucleotide excision repair. The C-terminus of RPA2 can specfically intereact with the DNA repair enzyme UNG2 and repair factors XPA and Rad52, each of which functions in a different repair pathway. In addition, this protein binds specifically to the SH2 domain of Stat3 in vivo, and overexpression of RPA2 corresponds to the augmented growth factor-stimulated tyrosine phosphorylation and transcription activities of Stat3. Recombinant human RPA2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Replication protein A 32 kDa subunit , REPA2, RPA32, RPA32, RP-A p32, RP-A p34. NCBI no.: NP_002937
    分子量
    31.7 kDa (293aa) confirmed by MALDI-TOF
    途径
    Telomere Maintenance, DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA
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