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POLH 抗体 (AA 20-320)

POLH 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3022621
发货至: 中国
  • 抗原 See all POLH 抗体
    POLH (Polymerase (DNA Directed), eta (POLH))
    抗原表位
    • 15
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    AA 20-320
    适用
    • 42
    • 12
    • 12
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 42
    • 3
    克隆类型
    • 44
    • 1
    多克隆
    标记
    • 18
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This POLH antibody is un-conjugated
    应用范围
    • 32
    • 13
    • 13
    • 12
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    序列
    QVEQRQNPHL RNKPCAVVQY KSWKGGGIIA VSYEARAFGV TRSMWADDAK KLCPDLLLAQ VRESRGKANL TKYREASVEV MEIMSRFAVI ERASIDEAYV DLTSAVQERL QKLQGQPISA DLLPSTYIEG LPQGPTTAEE TVQKEGMRKQ GLFQWLDSLQ IDNLTSPDLQ LTVGAVIVEE MRAAIERETG FQCSAGISHN KVLAKLACGL NKPNRQTLVS HGSVPQLFSQ MPIRKIRSLG GKLGASVIEI LGIEYMGELT QFTESQLQSH FGEKNGSWLY AMCRGIEHDP VKPRQLPKTI G
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Polyclonal Antibodies
    免疫原
    Recombinant fusion protein containing a sequence corresponding to amino acids 20-320 of human DNA polymerase eta (NP_006493.1).
    亚型
    IgG
    Top Product
    Discover our top product POLH Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000,IF,1:50 - 1:200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid freeze / thaw cycles
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    POLH (Polymerase (DNA Directed), eta (POLH))
    别名
    POLH (POLH 产品)
    别名
    POLH antibody, fc50a12 antibody, wu:fc50a12 antibody, zgc:136881 antibody, zgc:152642 antibody, RAD30 antibody, RAD30A antibody, XP-V antibody, XPV antibody, polymerase (DNA directed), eta S homeolog antibody, DNA polymerase eta antibody, polymerase (DNA directed), eta antibody, putative DNA polymerase eta antibody, polymerase (DNA directed), eta (RAD 30 related) antibody, polh.S antibody, POLH antibody, polh antibody, Tb10.70.6190 antibody, LINJ_21_0690 antibody, Polh antibody, LOC100443019 antibody
    背景
    This gene encodes a member of the Y family of specialized DNA polymerases. It copies undamaged DNA with a lower fidelity than other DNA-directed polymerases. However, it accurately replicates UV-damaged DNA, when thymine dimers are present, this polymerase inserts the complementary nucleotides in the newly synthesized DNA, thereby bypassing the lesion and suppressing the mutagenic effect of UV-induced DNA damage. This polymerase is thought to be involved in hypermutation during immunoglobulin class switch recombination. Mutations in this gene result in XPV, a variant type of xeroderma pigmentosum. Several transcript variants encoding different isoforms have been found for this gene.,POLH,RAD30,RAD30A,XP-V,XPV,Epigenetics & Nuclear Signaling,POLH
    分子量
    46 kDa/78 kDa
    基因ID
    5429
    UniProt
    Q9Y253
    途径
    DNA Damage Repair
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