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POLH 抗体

POLH 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7252888
发货至: 中国
  • 抗原 See all POLH 抗体
    POLH (Polymerase (DNA Directed), eta (POLH))
    适用
    • 42
    • 12
    • 11
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 43
    • 3
    克隆类型
    • 45
    • 1
    多克隆
    标记
    • 19
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This POLH antibody is un-conjugated
    应用范围
    • 33
    • 13
    • 13
    • 11
    • 7
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    产品特性
    Polyclonal Antibody
    纯化方法
    Antigen affinity purification
    免疫原
    Fusion protein of human POLH
    亚型
    IgG
    Top Product
    Discover our top product POLH Primary Antibody
  • 应用备注
    WB 1:500-1:2000, IHC 1:50-1:300, ELISA 1:5000-1:10000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.78 mg/mL
    缓冲液
    PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    POLH (Polymerase (DNA Directed), eta (POLH))
    别名
    POLH (POLH 产品)
    背景
    This gene encodes a member of the Y family of specialized DNA polymerases. It copies undamaged DNA with a lower fidelity than other DNA-directed polymerases. However, it accurately replicates UV-damaged DNA, when thymine dimers are present, this polymerase inserts the complementary nucleotides in the newly synthesized DNA, thereby bypassing the lesion and suppressing the mutagenic effect of UV-induced DNA damage. This polymerase is thought to be involved in hypermutation during immunoglobulin class switch recombination. Mutations in this gene result in XPV, a variant type of xeroderma pigmentosum. Several transcript variants encoding different isoforms have been found for this gene.
    分子量

    Observed_MW: Refer to figures

    Calculated_MW: 78 kDa

    UniProt
    Q9Y253
    途径
    DNA Damage Repair
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