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DDB1 抗体

KO Validated DDB1 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2857078
发货至: 中国
  • 抗原 See all DDB1 抗体
    DDB1 (Damage Specific DNA Binding Protein 1 (DDB1))
    适用
    • 43
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    宿主
    • 35
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    克隆类型
    • 35
    • 8
    多克隆
    标记
    • 32
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    • 1
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    This DDB1 antibody is un-conjugated
    应用范围
    • 28
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    Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
    交叉反应
    人, 小鼠
    产品特性
    Rabbit Polyclonal antibody to DDB1 (damage-specific DNA binding protein 1, 127 kDa)
    DDB1 antibody [N1N3]
    纯化方法
    Purified by antigen-affinity chromatography.
    质量等级
    KO Validated
    免疫原
    Recombinant protein encompassing a sequence within the center region of human DDB1. The exact sequence is proprietary.
    亚型
    IgG
    Top Product
    Discover our top product DDB1 Primary Antibody
  • 应用备注
    WB: 1:500-1:10000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    说明

    Positive Control: Mouse brain , HeLaS3 , Raji , 293T

    Validation: KO/KD

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal
    储存液
    Thimerosal (Merthiolate)
    注意事项
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原
    DDB1 (Damage Specific DNA Binding Protein 1 (DDB1))
    别名
    damage specific DNA binding protein 1 (DDB1 产品)
    别名
    DDBA antibody, UV-DDB1 antibody, XAP1 antibody, XPCE antibody, XPE antibody, XPE-BF antibody, DDB1 antibody, xpe antibody, ddba antibody, xap1 antibody, xpce antibody, xpe-bf antibody, uv-ddb1 antibody, ddb1 antibody, 127kDa antibody, AA408517 antibody, p127-Ddb1 antibody, damage specific DNA binding protein 1 antibody, damage-specific DNA binding protein 1, 127kDa antibody, DNA damage-binding protein 1 antibody, damage-specific DNA binding protein 1 antibody, DDB1 antibody, ddb1 antibody, LOC100187356 antibody, Ddb1 antibody, ddb-1 antibody
    背景
    This gene encodes the large subunit of DNA damage-binding protein which is a heterodimer composed of a large and a small subunit. This protein functions in nucleotide-excision repair. Its defective activity causes the repair defect in the patients with xeroderma pigmentosum complementation group E (XPE). However, it remains for mutation analysis to demonstrate whether the defect in XPE patients is in this gene or the gene encoding the small subunit. In addition, Best vitelliform mascular dystrophy is mapped to the same region as this gene on 11q, but no sequence alternations of this gene are demonstrated in Best disease patients.

    Cellular Localization: Cytoplasm , Nucleus
    分子量
    127 kDa
    基因ID
    1642
    UniProt
    Q16531
    途径
    DNA Damage Repair
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