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WNT1 抗体 (Center)

WNT1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2856226
发货至: 中国
  • 抗原 See all WNT1 抗体
    WNT1 (Wingless-Type MMTV Integration Site Family, Member 1 (WNT1))
    抗原表位
    • 15
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    Center
    适用
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    宿主
    • 54
    • 4
    克隆类型
    • 54
    • 4
    多克隆
    标记
    • 33
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    This WNT1 antibody is un-conjugated
    应用范围
    • 34
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    • 16
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    Western Blotting (WB)
    交叉反应
    小鼠, 大鼠
    交叉反应 (详细)
    Mouse (100 %), Rat (100 %)
    产品特性
    Rabbit Polyclonal antibody to WNT1 (proto-oncogene Wnt-1)
    Wnt1 antibody
    纯化方法
    Purified by antigen-affinity chromatography.
    免疫原
    Recombinant protein encompassing a sequence within the center region of human Wnt1. The exact sequence is proprietary.
    亚型
    IgG
    Top Product
    Discover our top product WNT1 Primary Antibody
  • 应用备注
    Suggested dilution Reference Western blot 1:1000-1:10000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceWestern blot1:1000-1:10000*
    说明

    Positive Control: WNT1 transfected 293T lysate

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.82 mg/mL
    缓冲液
    0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
    储存液
    Thimerosal (Merthiolate)
    注意事项
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原
    WNT1 (Wingless-Type MMTV Integration Site Family, Member 1 (WNT1))
    别名
    Wnt1 (WNT1 产品)
    别名
    Xint-1 antibody, Xwnt1 antibody, int-1 antibody, int1 antibody, wnt-1 antibody, wnt1-a antibody, Int-1 antibody, Wnt-1 antibody, sw antibody, swaying antibody, BMND16 antibody, INT1 antibody, OI15 antibody, Int1 antibody, WNT-1 antibody, sb:eu647 antibody, zgc:194464 antibody, zgc:194478 antibody, WNT1 antibody, Wnt family member 1 antibody, Wnt family member 1 L homeolog antibody, wingless-type MMTV integration site family, member 1 antibody, WNT1 antibody, wnt1.L antibody, Wnt1 antibody, wnt1 antibody
    背景
    The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is very conserved in evolution, and the protein encoded by this gene is known to be 98 % identical to the mouse Wnt1 protein at the amino acid level. The studies in mouse indicate that the Wnt1 protein functions in the induction of the mesencephalon and cerebellum. This gene was originally considered as a candidate gene for Joubert syndrome, an autosomal recessive disorder with cerebellar hypoplasia as a leading feature. However, further studies suggested that the gene mutations might not have a significant role in Joubert syndrome. This gene is clustered with another family member, WNT10B, in the chromosome 12q13 region.

    Cellular Localization: Secreted , extracellular space , extracellular matrix
    分子量
    41 kDa
    基因ID
    7471
    途径
    WNT signaling, Dopaminergic Neurogenesis
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