KDELR2 抗体 (Middle Region)
-
- 抗原 See all KDELR2 抗体
- KDELR2 (KDEL (Lys-Asp-Glu-Leu) Endoplasmic Reticulum Protein Retention Receptor 2 (KDELR2))
-
抗原表位
- Middle Region
-
适用
- 人
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This KDELR2 antibody is un-conjugated
-
应用范围
- Western Blotting (WB)
- 序列
- PVGGLSFLVN HDFSPLEYSR ERSSVCQHKC QRPSPASVLQ GARTEFLPQQ
- 预测反应
- Human: 100%
- 产品特性
- This is a rabbit polyclonal antibody against KDELR2. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of Human KDELR2
- Top Product
- Discover our top product KDELR2 Primary Antibody
-
-
- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
-
Antigen size: 186 AA
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
- 抗原
- KDELR2 (KDEL (Lys-Asp-Glu-Leu) Endoplasmic Reticulum Protein Retention Receptor 2 (KDELR2))
- 别名
- KDELR2 (KDELR2 产品)
- 别名
- kdelr2 antibody, ELP-1 antibody, ERD2.2 antibody, 1110007A14Rik antibody, kdelr1-a antibody, KDEL endoplasmic reticulum protein retention receptor 2 L homeolog antibody, KDEL endoplasmic reticulum protein retention receptor 2 antibody, KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 antibody, KDEL endoplasmic reticulum protein retention receptor 1 L homeolog antibody, kdelr2.L antibody, KDELR2 antibody, Kdelr2 antibody, kdelr1.L antibody
- 背景
-
Retention of resident soluble proteins in the lumen of the endoplasmic reticulum (ER) is achieved in both yeast and animal cells by their continual retrieval from the cis-Golgi, or a pre-Golgi compartment. Sorting of these proteins is dependent on a C-terminal tetrapeptide signal, usually lys-asp-glu-leu (KDEL) in animal cells, and his-asp-glu-leu (HDEL) in S. cerevisiae. This process is mediated by a receptor that recognizes, and binds the tetrapeptide-containing protein, and returns it to the ER. In yeast, the sorting receptor encoded by a single gene, ERD2, is a seven-transmembrane protein. Unlike yeast, several human homologs of the ERD2 gene, constituting the KDEL receptor gene family, have been described. KDELR2 was the second member of the family to be identified, and it encodes a protein which is 83 % identical to the KDELR1 gene product. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Alias Symbols: ELP-1, ERD2.2
Protein Interaction Partner: UBC, ELAVL1, SERINC3,
Protein Size: 186 - 分子量
- 21 kDa
- 基因ID
- 11014
- NCBI登录号
- NM_001100603, NP_001094073
- UniProt
- P33947
- 途径
- Maintenance of Protein Location
-