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KDELR2 抗体 (C-Term)

KDELR2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5536626
发货至: 中国
  • 抗原 See all KDELR2 抗体
    KDELR2 (KDEL (Lys-Asp-Glu-Leu) Endoplasmic Reticulum Protein Retention Receptor 2 (KDELR2))
    抗原表位
    • 7
    • 7
    • 7
    • 4
    • 2
    • 1
    • 1
    • 1
    AA 183-211, C-Term
    适用
    • 23
    • 7
    • 7
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 23
    克隆类型
    • 23
    多克隆
    标记
    • 13
    • 2
    • 2
    • 2
    • 2
    • 2
    This KDELR2 antibody is un-conjugated
    应用范围
    • 23
    • 19
    • 18
    • 8
    • 5
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This KDELR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 183-211 amino acids from the C-terminal region of human KDELR2.
    亚型
    Ig Fraction
    Top Product
    Discover our top product KDELR2 Primary Antibody
  • 应用备注
    For WB starting dilution is: 1:1000

    For IHC-P starting dilution is: 1:10~50
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.5 mg/mL
    缓冲液
    Supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原
    KDELR2 (KDEL (Lys-Asp-Glu-Leu) Endoplasmic Reticulum Protein Retention Receptor 2 (KDELR2))
    别名
    KDELR2 (KDELR2 产品)
    别名
    kdelr2 antibody, ELP-1 antibody, ERD2.2 antibody, 1110007A14Rik antibody, kdelr1-a antibody, KDEL endoplasmic reticulum protein retention receptor 2 L homeolog antibody, KDEL endoplasmic reticulum protein retention receptor 2 antibody, KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 antibody, KDEL endoplasmic reticulum protein retention receptor 1 L homeolog antibody, kdelr2.L antibody, KDELR2 antibody, Kdelr2 antibody, kdelr1.L antibody
    背景
    Retention of resident soluble proteins in the lumen of the endoplasmic reticulum (ER) is achieved in both yeast and animal cells by their continual retrieval from the cis-Golgi, or a pre-Golgi compartment. Sorting of these proteins is dependent on a C-terminal tetrapeptide signal, usually lys-asp-glu-leu (KDEL) in animal cells, and his-asp-glu-leu (HDEL) in S. cerevisiae. This process is mediated by a receptor that recognizes, and binds the tetrapeptide-containing protein, and returns it to the ER. In yeast, the sorting receptor encoded by a single gene, ERD2, is a seven-transmembrane protein. Unlike yeast, several human homologs of the ERD2 gene, constituting the KDEL receptor gene family, have been described. KDELR2 was the second member of the family to be identified, and it encodes a protein which is 83 % identical to the KDELR1 gene product. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq].
    分子量
    24 kDa
    基因ID
    11014
    UniProt
    P33947
    途径
    Maintenance of Protein Location
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