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KDELR2 抗体 (C-Term)

KDELR2 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN953024
发货至: 中国
  • 抗原 See all KDELR2 抗体
    KDELR2 (KDEL (Lys-Asp-Glu-Leu) Endoplasmic Reticulum Protein Retention Receptor 2 (KDELR2))
    抗原表位
    • 8
    • 7
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    AA 182-211, C-Term
    适用
    • 23
    • 7
    • 7
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 23
    克隆类型
    • 23
    多克隆
    标记
    • 13
    • 2
    • 2
    • 2
    • 2
    • 2
    This KDELR2 antibody is un-conjugated
    应用范围
    • 23
    • 19
    • 18
    • 8
    • 5
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    特异性
    This antibody recognizes Human KDEL Receptor 2 / KDELR2 (C-term).
    纯化方法
    Protein A column, followed by peptide affinity purification
    免疫原
    KLH conjugated synthetic peptide between 182-211 amino acids from the C-terminal region of human KDELR2
    亚型
    Ig Fraction
    Top Product
    Discover our top product KDELR2 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.25 mg/mL
    缓冲液
    PBS containing 0.09 % (W/V) Sodium Azide as preservative
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    KDELR2 (KDEL (Lys-Asp-Glu-Leu) Endoplasmic Reticulum Protein Retention Receptor 2 (KDELR2))
    别名
    KDEL Receptor 2 / KDELR2 (KDELR2 产品)
    别名
    kdelr2 antibody, ELP-1 antibody, ERD2.2 antibody, 1110007A14Rik antibody, kdelr1-a antibody, KDEL endoplasmic reticulum protein retention receptor 2 L homeolog antibody, KDEL endoplasmic reticulum protein retention receptor 2 antibody, KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 antibody, KDEL endoplasmic reticulum protein retention receptor 1 L homeolog antibody, kdelr2.L antibody, KDELR2 antibody, Kdelr2 antibody, kdelr1.L antibody
    背景
    Retention of resident soluble proteins in the lumen of the endoplasmic reticulum (ER) is achieved in both yeast and animal cells by their continual retrieval from the cis-Golgi, or a pre-Golgi compartment. Sorting of these proteins is dependent on a C-terminal tetrapeptide signal, usually lys-asp-glu-leu (KDEL) in animal cells, and his-asp-glu-leu (HDEL) in S. cerevisiae. This process is mediated by a receptor that recognizes, and binds the tetrapeptide-containing protein, and returns it to the ER. In yeast, the sorting receptor encoded by a single gene, ERD2, is a seven-transmembrane protein. Unlike yeast, several human homologs of the ERD2 gene, constituting the KDEL receptor gene family, have been described. KDELR2 was the second member of the family to be identified, and it encodes a protein which is 83 % identical to the KDELR1 gene product. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq].Synonyms: ELP-1, ER lumen protein retaining receptor 2, ERD2-like protein 1, ERD2.2, KDEL endoplasmic reticulum protein retention receptor 2
    分子量
    24422 Da
    基因ID
    11014
    NCBI登录号
    NP_001094073
    途径
    Maintenance of Protein Location
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