RFC4 抗体 (Middle Region)
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- 抗原 See all RFC4 抗体
- RFC4 (Replication Factor C (Activator 1) 4, 37kDa (RFC4))
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抗原表位
- Middle Region
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适用
- 人, 大鼠, 小鼠, 犬, Pig, Cow, 马, 豚鼠, 兔
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This RFC4 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- DKLEAVVKDL IDEGHAATQL VNQLHDVVVE NNLSDKQKSI ITEKLAEVDK
- 预测反应
- Cow: 93%, Dog: 86%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 93%, Rat: 100%
- 产品特性
- This is a rabbit polyclonal antibody against RFC4. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human RFC4
- Top Product
- Discover our top product RFC4 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 363 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- RFC4 (Replication Factor C (Activator 1) 4, 37kDa (RFC4))
- 别名
- RFC4 (RFC4 产品)
- 别名
- 44.t00003 antibody, 21.m03053 antibody, rfc4 antibody, A1 antibody, AI894123 antibody, AU040575 antibody, RFC37 antibody, rfc2 antibody, replication factor C subunit 4 antibody, Replication factor C subunit 4 antibody, replication factor C (activator 1) 4 antibody, replication factor C subunit 4 L homeolog antibody, PFL2005w antibody, EHI_167150 antibody, TP03_0432 antibody, Tb11.01.1310 antibody, BBOV_IV002210 antibody, rfc4 antibody, rfc-4 antibody, Rfc4 antibody, RFC4 antibody, rfc4.L antibody
- 背景
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The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins proliferating cell nuclear antigen (PCNA) and activator 1. This subunit may be involved in the elongation of the multiprimed DNA template.The elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon requires the accessory proteins proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). RFC, also named activator 1, is a protein complex consisting of five distinct subunits of 140, 40, 38, 37, and 36 kD. This gene encodes the 37 kD subunit. This subunit forms a core complex with the 36 and 40 kDa subunits. The core complex possesses DNA-dependent ATPase activity, which was found to be stimulated by PCNA in an in vitro system. Alternatively spliced transcript variants encoding the same protein have been reported.
Alias Symbols: A1, MGC27291, RFC37
Protein Interaction Partner: RNF41, UBC, RFC5, PCNA, TP53, SUMO2, RPA3, RPA2, RPA1, RNF2, C14orf166, RTCB, RPL26L1, DIMT1, NELFB, EDC4, IGF2BP3, EIF2B2, EIF2B3, YBX3, QARS, NMT1, HNRNPM, MRE11A, ILF2, HNRNPU, FLII, FKBP3, EPRS, DHX9, DDX1, ABCF1, PARK2, TARDBP, MPG, RFC2, MYC, FN1, P
Protein Size: 363 - 分子量
- 40 kDa
- 基因ID
- 5984
- NCBI登录号
- NM_002916, NP_002907
- UniProt
- P35249
- 途径
- Telomere Maintenance, DNA Damage Repair, DNA Replication, Synthesis of DNA
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