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RFC4 产品

(Replication Factor C (Activator 1) 4, 37kDa (RFC4))

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The elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon requires the accessory proteins proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). RFC, also named activator 1, is a protein complex consisting of five distinct subunits of 140, 40, 38, 37, and 36 kD. This gene encodes the 37 kD subunit. This subunit forms a core complex with the 36 and 40 kDa subunits. The core complex possesses DNA-dependent ATPase activity, which was found to be stimulated by PCNA in an in vitro system. Alternatively spliced transcript variants encoding the same protein have been reported. [provided by RefSeq, Jul 2008].

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Featured RFC4 Categories

RFC4 抗体

High quality antibodies with extensive validation data.

RFC4 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended RFC4 抗体

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Reactivity
Application
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Datasheet
Reactivity Human, Rat
Application WB, IF, IHC
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  • (6)
Cat. No. ABIN7261451
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC (p), RNAi
Validations
  • (6)
Cat. No. ABIN562635
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IF, IP
Validations
  • (7)
Cat. No. ABIN6146881
Quantity 100 μL
Datasheet Datasheet

Recommended RFC4 ELISA试剂盒

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Reactivity
Analytical Method
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Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6232216
Quantity 96 tests
Datasheet Datasheet

Recommended RFC4 蛋白

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Reactivity
Source
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Source Wheat germ
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Cat. No. ABIN1317845
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
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Cat. No. ABIN1317843
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
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Cat. No. ABIN3087127
Quantity 1 mg
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Latest Publications for our RFC4 Products

Jiang, Zhang, Chen, Lei, Zhang, Wang, Jin, Lan, Zhou, Huang, Li, Liu, Gao, Xie, Zhou, Nice, Peng, Cao, Wei, Wang, Huang: "Regorafenib induces lethal autophagy arrest by stabilizing PSAT1 in glioblastoma." in: Autophagy, pp. 1-17, (2019) (PubMed).

Wang, Zhang, Lei, Li, Jiang, Lan, Liu, Chen, Gao, Xie, Chen, Zhu, Liu, Xie, Peng, Nice, Wu, Huang, Wei: "Identification of ANXA2 (annexin A2) as a specific bleomycin target to induce pulmonary fibrosis by impeding TFEB-mediated autophagic flux." in: Autophagy, pp. 1-14, (2017) (PubMed).

Redondo-Muñoz, Rodríguez, Silió, Pérez-García, Valpuesta, Carrera: "Phosphoinositide 3-kinase beta controls replication factor C assembly and function." in: Nucleic acids research, Vol. 41, Issue 2, pp. 855-68, (2013) (PubMed).

Collis, Schwaninger, Ntambi, Keller, Nelson, Dillehay, Deweese: "Evasion of early cellular response mechanisms following low level radiation-induced DNA damage." in: The Journal of biological chemistry, Vol. 279, Issue 48, pp. 49624-32, (2004) (PubMed).

Synonyms and alternative names related to RFC4

replication factor C subunit 4 (PFL2005w), Replication factor C subunit 4 (EHI_167150), replication factor C subunit 4 (TP03_0432), replication factor C subunit 4 (Tb11.01.1310), replication factor C subunit 4 (BBOV_IV002210), replication factor C subunit 4 (rfc4), Replication factor C subunit 4 (rfc-4), replication factor C (activator 1) 4 (Rfc4), replication factor C subunit 4 (Rfc4), replication factor C subunit 4 (RFC4), replication factor C subunit 4 L homeolog (rfc4.L), 21.m03053, 44.t00003, A1, AI894123, AU040575, rfc2, rfc4, RFC37

Protein level used designations for RFC4

  • replication factor C subunit 4
  • Replication factor C subunit 4
  • activator 1 subunit 4
  • A1 37 kDa subunit
  • RF-C 37 kDa subunit
  • RFC 37 kDa subunit
  • activator 1 37 kDa subunit
  • replication factor C 37 kDa subunit
  • replication factor C p37 subunit
  • replication factor C 4
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