电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

RFFL 产品

(Ring Finger and FYVE-Like Domain Containing 1 (RFFL))

Categories

Has E3 ubiquitin protein ligase activity. Regulates the levels of CASP8 and CASP10 by targeting them for proteasomal degradation. Has anti-apoptotic activity. May bind phosphatidylinositol phosphates (By similarity). Overexpression slows protein traffic through recycling endosomes.

antibodies-online.com stands for high-quality research products. Search, find and order tools with extensive validation data, images, references. Our scientific customer service is always at your disposal if you have any questions about the selection or application of our products.

Featured RFFL Categories

RFFL 抗体

High quality antibodies with extensive validation data.

RFFL 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended RFFL 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, RNAi
Validations
  • (4)
Cat. No. ABIN566759
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7151117
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (5)
  • (1)
Cat. No. ABIN1881744
Quantity 400 μL
Datasheet Datasheet

Recommended RFFL ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6221029
Quantity 96 tests
Datasheet Datasheet

Recommended RFFL 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1317849
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1317851
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
Cat. No. ABIN3095003
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our RFFL Products

Hanuszkiewicz, Pittock, Humphries, Moll, Rosales, Molinaro, Moynagh, Lajoie, Valvano: "Identification of the flagellin glycosylation system in Burkholderia cenocepacia and the contribution of glycosylated flagellin to evasion of human innate immune responses." in: The Journal of biological chemistry, Vol. 289, Issue 27, pp. 19231-44, (2014) (PubMed).

Shimada, Miyagawa, Kawashima, Tanaka, Honda, Honda, Tokunaga: "An approach based on a genome-wide association study reveals candidate loci for narcolepsy." in: Human genetics, Vol. 128, Issue 4, pp. 433-41, (2010) (PubMed).

Newton-Cheh, Eijgelsheim, Rice, de Bakker, Yin, Estrada, Bis, Marciante, Rivadeneira, Noseworthy, Sotoodehnia, Smith, Rotter, Kors, Witteman, Hofman, Heckbert: "Common variants at ten loci influence QT interval duration in the QTGEN Study." in: Nature genetics, Vol. 41, Issue 4, pp. 399-406, (2009) (PubMed).

Hosgood, Zhang, Shen, Berndt, Vermeulen, Li, Yin, Yeager, Yuenger, Rothman, Chanock, Smith, Lan: "Association between genetic variants in VEGF, ERCC3 and occupational benzene haematotoxicity." in: Occupational and environmental medicine, Vol. 66, Issue 12, pp. 848-53, (2009) (PubMed).

Liao, Xiao, Tchikov, Fujita, Yang, Wincovitch, Garfield, Conze, El-Deiry, Schütze, Srinivasula: "CARP-2 is an endosome-associated ubiquitin ligase for RIP and regulates TNF-induced NF-kappaB activation." in: Current biology : CB, Vol. 18, Issue 9, pp. 641-9, (2008) (PubMed).

Yang, Dicker, Chen, El-Deiry: "CARPs enhance p53 turnover by degrading 14-3-3sigma and stabilizing MDM2." in: Cell cycle (Georgetown, Tex.), Vol. 7, Issue 5, pp. 670-82, (2008) (PubMed).

McDonald, El-Deiry: "Suppression of caspase-8- and -10-associated RING proteins results in sensitization to death ligands and inhibition of tumor cell growth." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 16, pp. 6170-5, (2004) (PubMed).

Coumailleau, Das, Alcover, Raposo, Vandormael-Pournin, Le Bras, Baldacci, Dautry-Varsat, Babinet, Cohen-Tannoudji: "Over-expression of Rififylin, a new RING finger and FYVE-like domain-containing protein, inhibits recycling from the endocytic recycling compartment." in: Molecular biology of the cell, Vol. 15, Issue 10, pp. 4444-56, (2004) (PubMed).

Tibbetts, Shiozaki, Gu, McDonald, El-Deiry, Shi: "Crystal structure of a FYVE-type zinc finger domain from the caspase regulator CARP2." in: Structure (London, England : 1993), Vol. 12, Issue 12, pp. 2257-63, (2004) (PubMed).

Synonyms and alternative names related to RFFL

ring finger and FYVE like domain containing E3 ubiquitin protein ligase (RFFL), ring finger and FYVE-like domain containing E3 ubiquitin protein ligase L homeolog (rffl.L), ring finger and FYVE-like domain containing 1 (Rffl), ring finger and FYVE like domain containing protein (Rffl), ring finger and FYVE-like domain containing E3 ubiquitin protein ligase (Rffl), 1700051E09Rik, 4930516L10Rik, BG080975, CARP-2, Carp2, CARP2, FRING, MGC84042, RFFL, Rffl, RIFIFYLIN, RNF34L, RNF189

Protein level used designations for RFFL

  • E3 ubiquitin-protein ligase rififylin
  • ring finger and FYVE-like domain containing 1
  • rififylin
  • e3 ubiquitin-protein ligase rififylin-like
  • RING finger and FYVE-like domain-containing protein 1
  • fring
  • FYVE-RING finger protein SAKURA
  • RING finger protein 189
  • caspase regulator CARP2
  • caspases-8 and -10-associated RING finger protein 2
  • FYVE-RING finger protein Sakura
  • RING finger protein SAKURA
  • ring finger and FYVE like domain containing protein
You are here:
客服