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SLC5A8 抗体 (Middle Region)

SLC5A8 适用: 人, 小鼠, 大鼠, 兔 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2781721
发货至: 中国
  • 抗原 See all SLC5A8 抗体
    SLC5A8 (Solute Carrier Family 5 (Iodide Transporter), Member 8 (SLC5A8))
    抗原表位
    • 14
    • 12
    • 8
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    • 33
    • 27
    • 23
    • 5
    • 5
    • 5
    人, 小鼠, 大鼠, 兔
    宿主
    • 44
    克隆类型
    • 44
    多克隆
    标记
    • 11
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SLC5A8 antibody is un-conjugated
    应用范围
    • 39
    • 21
    • 3
    • 2
    • 1
    Western Blotting (WB)
    序列
    GILVPFANSI GALVGLMAGF AISLWVGIGA QIYPPLPERT LPLHLDIQGC
    预测反应
    Human: 100%, Mouse: 83%, Rabbit: 92%, Rat: 91%
    产品特性
    This is a rabbit polyclonal antibody against SLC5A8. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human SLC5A8
    Top Product
    Discover our top product SLC5A8 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 610 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Elangovan, Pathania, Ramachandran, Ananth, Padia, Srinivas, Babu, Hawthorn, Schoenlein, Boettger, Smith, Prasad, Ganapathy, Thangaraju: "Molecular mechanism of SLC5A8 inactivation in breast cancer." in: Molecular and cellular biology, Vol. 33, Issue 19, pp. 3920-35, (2013) (PubMed).

    Babu, Ramachandran, CoothanKandaswamy, Elangovan, Prasad, Ganapathy, Thangaraju: "Role of SLC5A8, a plasma membrane transporter and a tumor suppressor, in the antitumor activity of dichloroacetate." in: Oncogene, Vol. 30, Issue 38, pp. 4026-37, (2011) (PubMed).

    Zhang, Bao, Yang, Wu, Yu, Huang, Sun, Zheng, Li: "Activin A induces SLC5A8 expression through the Smad3 signaling pathway in human colon cancer RKO cells." in: The international journal of biochemistry & cell biology, Vol. 42, Issue 12, pp. 1964-72, (2010) (PubMed).

  • 抗原
    SLC5A8 (Solute Carrier Family 5 (Iodide Transporter), Member 8 (SLC5A8))
    别名
    SLC5A8 (SLC5A8 产品)
    别名
    Ait antibody, SMCT antibody, SMCT1 antibody, AIT antibody, RGD1564146 antibody, solute carrier family 5 (iodide transporter), member 8 antibody, solute carrier family 5 member 8 antibody, Slc5a8 antibody, SLC5A8 antibody
    背景
    SLC5A8 has been shown to transport iodide by a passive mechanism (Rodriguez et al., 2002 [PubMed 12107270]) and monocarboxylates and short-chain fatty acids by a sodium-coupled mechanism (Gopal et al., 2004 [PubMed 15322102]). In kidney, SLC5A8 functions
    Alias Symbols: AIT, MGC125354, SMCT, SMCT1
    Protein Size: 610
    分子量
    66 kDa
    基因ID
    160728
    NCBI登录号
    NM_145913, NP_666018
    UniProt
    Q8N695
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