SLC5A8 抗体 (Middle Region)
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- 抗原 See all SLC5A8 抗体
- SLC5A8 (Solute Carrier Family 5 (Iodide Transporter), Member 8 (SLC5A8))
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抗原表位
- Middle Region
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适用
- 人, 小鼠, 大鼠, 兔
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SLC5A8 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- GILVPFANSI GALVGLMAGF AISLWVGIGA QIYPPLPERT LPLHLDIQGC
- 预测反应
- Human: 100%, Mouse: 83%, Rabbit: 92%, Rat: 91%
- 产品特性
- This is a rabbit polyclonal antibody against SLC5A8. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human SLC5A8
- Top Product
- Discover our top product SLC5A8 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 610 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Molecular mechanism of SLC5A8 inactivation in breast cancer." in: Molecular and cellular biology, Vol. 33, Issue 19, pp. 3920-35, (2013) (PubMed).
: "Role of SLC5A8, a plasma membrane transporter and a tumor suppressor, in the antitumor activity of dichloroacetate." in: Oncogene, Vol. 30, Issue 38, pp. 4026-37, (2011) (PubMed).
: "Activin A induces SLC5A8 expression through the Smad3 signaling pathway in human colon cancer RKO cells." in: The international journal of biochemistry & cell biology, Vol. 42, Issue 12, pp. 1964-72, (2010) (PubMed).
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Molecular mechanism of SLC5A8 inactivation in breast cancer." in: Molecular and cellular biology, Vol. 33, Issue 19, pp. 3920-35, (2013) (PubMed).
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- 抗原
- SLC5A8 (Solute Carrier Family 5 (Iodide Transporter), Member 8 (SLC5A8))
- 别名
- SLC5A8 (SLC5A8 产品)
- 别名
- Ait antibody, SMCT antibody, SMCT1 antibody, AIT antibody, RGD1564146 antibody, solute carrier family 5 (iodide transporter), member 8 antibody, solute carrier family 5 member 8 antibody, Slc5a8 antibody, SLC5A8 antibody
- 背景
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SLC5A8 has been shown to transport iodide by a passive mechanism (Rodriguez et al., 2002 [PubMed 12107270]) and monocarboxylates and short-chain fatty acids by a sodium-coupled mechanism (Gopal et al., 2004 [PubMed 15322102]). In kidney, SLC5A8 functions
Alias Symbols: AIT, MGC125354, SMCT, SMCT1
Protein Size: 610 - 分子量
- 66 kDa
- 基因ID
- 160728
- NCBI登录号
- NM_145913, NP_666018
- UniProt
- Q8N695
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