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SLC5A8 抗体 (AA 540-610)

SLC5A8 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7169960
发货至: 中国
  • 抗原 See all SLC5A8 抗体
    SLC5A8 (Solute Carrier Family 5 (Iodide Transporter), Member 8 (SLC5A8))
    抗原表位
    • 14
    • 12
    • 8
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 540-610
    适用
    • 34
    • 27
    • 24
    • 5
    • 5
    • 5
    • 1
    宿主
    • 44
    克隆类型
    • 44
    多克隆
    标记
    • 11
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SLC5A8 antibody is un-conjugated
    应用范围
    • 40
    • 20
    • 3
    • 1
    • 1
    ELISA, Immunofluorescence (IF)
    交叉反应
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human Sodium-coupled monocarboxylate transporter 1 protein (540-610AA)
    亚型
    IgG
    Top Product
    Discover our top product SLC5A8 Primary Antibody
  • 应用备注
    Recommended dilution: IF:1:50-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    SLC5A8 (Solute Carrier Family 5 (Iodide Transporter), Member 8 (SLC5A8))
    别名
    SLC5A8 (SLC5A8 产品)
    别名
    Ait antibody, SMCT antibody, SMCT1 antibody, AIT antibody, RGD1564146 antibody, solute carrier family 5 (iodide transporter), member 8 antibody, solute carrier family 5 member 8 antibody, Slc5a8 antibody, SLC5A8 antibody
    背景

    Background: Acts as an electrogenic sodium (Na(+)) and chloride (Cl-)-dependent sodium-coupled solute transporter, including transport of monocarboxylates (short-chain fatty acids including L-lactate, D-lactate, pyruvate, acetate, propionate, valerate and butyrate), lactate, mocarboxylate drugs (nicotinate, benzoate, salicylate and 5-aminosalicylate) and ketone bodies (beta-D-hydroxybutyrate, acetoacetate and alpha-ketoisocaproate), with a Na(+):substrate stoichiometry of between 4:1 and 2:1. Catalyzes passive carrier mediated diffusion of iodide. Mediates iodide transport from the thyrocyte into the colloid lumen through the apical membrane. May be responsible for the absorption of D-lactate and monocarboxylate drugs from the intestinal tract. Acts as a tumor suppressor, suppressing colony formation in colon cancer, prostate cancer and glioma cell lines. May play a critical role in the entry of L-lactate and ketone bodies into neurons by a process driven by an electrochemical Na(+) gradient and hence contribute to the maintenance of the energy status and function of neurons.

    Aliases: AIT antibody, Apical iodide transporter antibody, Electrogenic sodium monocarboxylate cotransporter antibody, MGC125354 antibody, SC5A8_HUMAN antibody, SLC5A8 antibody, SMCT antibody, SMCT1 antibody, sodium coupled monocarboxylate transporter 1 antibody, Sodium iodide related cotransporter antibody, Sodium iodide-related cotransporter antibody, Sodium-coupled monocarboxylate transporter 1 antibody, solute carrier family 5 iodide transporter member 8 antibody, Solute carrier family 5 member 8 antibody

    UniProt
    Q8N695
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