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SLC5A8 产品

(Solute Carrier Family 5 (Iodide Transporter), Member 8 (SLC5A8))

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SLC5A8 has been shown to transport iodide by a passive mechanism (Rodriguez et al., 2002 [PubMed 12107270]) and monocarboxylates and short-chain fatty acids by a sodium-coupled mechanism (Gopal et al., 2004 [PubMed 15322102]). In kidney, SLC5A8 functions as a high-affinity sodium-coupled lactate transporter involved in reabsorption of lactate and maintenance of blood lactate levels (Thangaraju et al., 2006 [PubMed 16873376]).[supplied by OMIM, Dec 2008].

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Featured SLC5A8 Categories

SLC5A8 抗体

High quality antibodies with extensive validation data.

Recommended SLC5A8 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Application WB
Validations
  • (1)
  • (1)
Cat. No. ABIN1881812
Quantity 400 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rabbit, Rat
Application WB
Validations
  • (3)
  • (2)
Cat. No. ABIN2781721
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC
Validations
  • (3)
Cat. No. ABIN7043734
Quantity 0.2 mL
Datasheet Datasheet

Recommended SLC5A8 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6970346
Quantity 96 tests
Datasheet Datasheet

Recommended SLC5A8 蛋白

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Reactivity
Source
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Cat. No.
Quantity
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Reactivity Human
Source Escherichia coli (E. coli)
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Cat. No. ABIN7125168
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3116561
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3136310
Quantity 1 mg
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Latest Publications for our SLC5A8 Products

Konstantakou, Voutsinas, Velentzas, Basogianni, Paronis, Balafas, Kostomitsopoulos, Syrigos, Anastasiadou, Stravopodis: "3-BrPA eliminates human bladder cancer cells with highly oncogenic signatures via engagement of specific death programs and perturbation of multiple signaling and metabolic determinants." in: Molecular cancer, Vol. 14, pp. 135, (2015) (PubMed).

Nedjadi, Moran, Al-Rammahi, Shirazi-Beechey: "Characterization of butyrate transport across the luminal membranes of equine large intestine." in: Experimental physiology, Vol. 99, Issue 10, pp. 1335-47, (2014) (PubMed).

Elangovan, Pathania, Ramachandran, Ananth, Padia, Srinivas, Babu, Hawthorn, Schoenlein, Boettger, Smith, Prasad, Ganapathy, Thangaraju: "Molecular mechanism of SLC5A8 inactivation in breast cancer." in: Molecular and cellular biology, Vol. 33, Issue 19, pp. 3920-35, (2013) (PubMed).

Babu, Ramachandran, CoothanKandaswamy, Elangovan, Prasad, Ganapathy, Thangaraju: "Role of SLC5A8, a plasma membrane transporter and a tumor suppressor, in the antitumor activity of dichloroacetate." in: Oncogene, Vol. 30, Issue 38, pp. 4026-37, (2011) (PubMed).

Cresci, Thangaraju, Mellinger, Liu, Ganapathy: "Colonic gene expression in conventional and germ-free mice with a focus on the butyrate receptor GPR109A and the butyrate transporter SLC5A8." in: Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, Vol. 14, Issue 3, pp. 449-61, (2010) (PubMed).

Zhang, Bao, Yang, Wu, Yu, Huang, Sun, Zheng, Li: "Activin A induces SLC5A8 expression through the Smad3 signaling pathway in human colon cancer RKO cells." in: The international journal of biochemistry & cell biology, Vol. 42, Issue 12, pp. 1964-72, (2010) (PubMed).

Synonyms and alternative names related to SLC5A8

solute carrier family 5 (iodide transporter), member 8 (Slc5a8), solute carrier family 5 member 8 (SLC5A8), solute carrier family 5 member 8 (Slc5a8), Ait, AIT, RGD1564146, SMCT, SMCT1

Protein level used designations for SLC5A8

  • apical iodide transporter , putative
  • electrogenic sodium monocarboxylate cotransporter
  • sodium-coupled monocarboxylate transporter 1
  • solute carrier family 5 member 8
  • sodium-dependent monocarboxylate cotransporter
  • apical iodide transporter
  • sodium iodide-related cotransporter
  • solute carrier family 5 (iodide transporter), member 8
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