SLC5A8 抗体 (AA 301-336) (AbBy Fluor® 350)
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北京 101111
Quick Overview for SLC5A8 抗体 (AA 301-336) (AbBy Fluor® 350) (ABIN915605)
抗原
See all SLC5A8 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 301-336
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交叉反应
- 大鼠
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预测反应
- Human,Mouse,Dog,Cow,Chicken
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human SLC5A8
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亚型
- IgG
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anti-Solute Carrier Family 5 (Iodide Transporter), Member 8 (SLC5A8) (AA 548-574), (C-Term) antibody
SLC5A8 适用: 小鼠 WB 宿主: 兔 Polyclonal RB40849 unconjugated
anti-Solute Carrier Family 5 (Iodide Transporter), Member 8 (SLC5A8) (Middle Region) antibodySLC5A8 适用: 人, 小鼠, 大鼠, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-Solute Carrier Family 5 (Iodide Transporter), Member 8 (SLC5A8) (AA 544-558), (Intracellular) antibodySLC5A8 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Solute Carrier Family 5 (Iodide Transporter), Member 8 (SLC5A8) (AA 301-400) antibodySLC5A8 适用: 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Solute Carrier Family 5 (Iodide Transporter), Member 8 (SLC5A8) (AA 540-610) antibodySLC5A8 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Solute Carrier Family 5 (Iodide Transporter), Member 8 (SLC5A8) (AA 579-609) antibodySLC5A8 适用: 人 WB 宿主: 兔 Polyclonal RB54852 unconjugated
anti-Solute Carrier Family 5 (Iodide Transporter), Member 8 (SLC5A8) (AA 431-480) antibodySLC5A8 适用: 人, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- IF(IHC-P) 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- SLC5A8 (Solute Carrier Family 5 (Iodide Transporter), Member 8 (SLC5A8))
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别名
- Slc5a8
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背景
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Synonyms: AIT, SMCT, SMCT1, Sodium-coupled monocarboxylate transporter 1, Apical iodide transporter, Electrogenic sodium monocarboxylate cotransporter, Sodium iodide-related cotransporter, Solute carrier family 5 member 8, SLC5A8
Background: Acts as an electrogenic sodium (Na(+)) and chloride (Cl-)-dependent sodium-coupled solute transporter, including transport of monocarboxylates (short-chain fatty acids including L-lactate, D-lactate, pyruvate, acetate, propionate, valerate and butyrate), lactate, mocarboxylate drugs (nicotinate, benzoate, salicylate and 5-aminosalicylate) and ketone bodies (beta-D-hydroxybutyrate, acetoacetate and alpha-ketoisocaproate), with a Na(+):substrate stoichiometry of between 4:1 and 2:1. Catalyzes passive carrier mediated diffusion of iodide. Mediates iodide transport from the thyrocyte into the colloid lumen through the apical membrane. May be responsible for the absorption of D-lactate and monocarboxylate drugs from the intestinal tract. Acts as a tumor suppressor, suppressing colony formation in colon cancer, prostate cancer and glioma cell lines. May play a critical role in the entry of L-lactate and ketone bodies into neurons by a process driven by an electrochemical Na(+) gradient and hence contribute to the maintenance of the energy status and function of neurons.
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基因ID
- 160728
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UniProt
- Q8N695
抗原
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