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NFAT1 抗体 (C-Term)

NFAT1 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 豚鼠, 兔, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2780879
发货至: 中国
  • 抗原 See all NFAT1 抗体
    NFAT1 (Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 2 (NFAT1))
    抗原表位
    • 24
    • 23
    • 15
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 99
    • 36
    • 23
    • 6
    • 5
    • 4
    • 4
    • 4
    • 4
    • 2
    • 1
    人, 小鼠, 大鼠, 犬, Cow, 马, 豚鼠, 兔, 斑马鱼
    宿主
    • 97
    • 5
    • 1
    克隆类型
    • 91
    • 12
    多克隆
    标记
    • 38
    • 7
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
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    • 1
    This NFAT1 antibody is un-conjugated
    应用范围
    • 74
    • 28
    • 14
    • 13
    • 13
    • 11
    • 10
    • 8
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    序列
    PTVIQQQNAT SQRAAKNGPP VSDQKEVLPA GVTIKQEQNL DQTYLDDVNE
    预测反应
    Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 85%
    产品特性
    This is a rabbit polyclonal antibody against NFATC2. It was validated on Western Blot.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the C terminal region of human NFATC2
    Top Product
    Discover our top product NFAT1 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 925 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    NFAT1 (Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 2 (NFAT1))
    别名
    NFATC2 (NFAT1 产品)
    别名
    NFATC2 antibody, AI607462 antibody, NF-ATc2 antibody, NFAT1 antibody, NFAT1-D antibody, Nfatp antibody, NFATP antibody, nuclear factor of activated T-cells 2 antibody, nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2 antibody, NFATC2 antibody, nfatc2 antibody, Nfatc2 antibody
    背景
    This gene is a member of the nuclear factor of activated T cells (NFAT) family. The product of this gene is a DNA-binding protein with a REL-homology region (RHR) and an NFAT-homology region (NHR). This protein is present in the cytosol and only translocates to the nucleus upon T cell receptor (TCR) stimulation, where it becomes a member of the nuclear factors of activated T cells transcription complex. This complex plays a central role in inducing gene transcription during the immune response. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
    Alias Symbols: NFAT1, NFATP
    Protein Interaction Partner: GNB2, USP22, UBC, TNPO1, CSE1L, LRRK2, IQGAP1, PPP2R1A, JUN, NFATC2, CREBBP, IRF2BP2, TFAP4, HNRNPA1, TAF9, TUBA1A, KPNB1, SUV39H1, MAPK9, MAPK8, MED31, NFATC2IP, EP300, IRF4, PPP3R1, YWHAZ, PIN1, MEF2D, FOXP3, VIM, PRKCZ, YWHAQ, EGR4, EGR1, PPP3CB,
    Protein Size: 925
    分子量
    100 kDa
    基因ID
    4773
    NCBI登录号
    NM_173091, NP_775114
    UniProt
    Q13469
    途径
    RTK signaling, WNT signaling, Fc-epsilon Receptor Signaling Pathway, VEGF Signaling, BCR Signaling
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