AATF 抗体 (C-Term)
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- 抗原 See all AATF 抗体
- AATF (Apoptosis Antagonizing Transcription Factor (AATF))
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抗原表位
- C-Term
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适用
- 人, 小鼠, 大鼠, 犬, 马, 兔, 豚鼠, Cow, Saccharomyces cerevisiae, 斑马鱼
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This AATF antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- PNDQVAMGRQ WLAIQKLRSK IHKKVDRKAS KGRKLRFHVL SKLLSFMAPI
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 92%, Zebrafish: 86%
- 产品特性
- This is a rabbit polyclonal antibody against AATF. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Protein A purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human AATF
- Top Product
- Discover our top product AATF Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 560 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- AATF (Apoptosis Antagonizing Transcription Factor (AATF))
- 别名
- AATF (AATF 产品)
- 别名
- AATF antibody, ded antibody, che1 antibody, che-1 antibody, cb109 antibody, sb:cb109 antibody, wu:fc13d05 antibody, zgc:162071 antibody, CHE-1 antibody, CHE1 antibody, DED antibody, 4933415H02Rik antibody, 5830465M17Rik antibody, Che-1 antibody, Trb antibody, Ded antibody, apoptosis antagonizing transcription factor antibody, Apoptosis antagonizing transcription factor antibody, apoptosis antagonizing transcription factor S homeolog antibody, AATF antibody, aatf antibody, BFR2 antibody, NAEGRDRAFT_56916 antibody, Aatf antibody, aatf.S antibody
- 背景
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The AATF gene encodes a protein that was identified on the basis of its interaction with MAP3K12/DLK, a protein kinase known to be involved in the induction of cell apoptosis. This gene product contains a leucine zipper, which is a characteristic motif of transcription factors, and was shown to exhibit strong transactivation activity when fused to Gal4 DNA binding domain. Overexpression of this gene interfered with MAP3K12 induced apoptosis.The protein encoded by this gene was identified on the basis of its interaction with MAP3K12/DLK, a protein kinase known to be involved in the induction of cell apoptosis. This gene product contains a leucine zipper, which is a characteristic motif of transcription factors, and was shown to exhibit strong transactivation activity when fused to Gal4 DNA binding domain. Overexpression of this gene interfered with MAP3K12 induced apoptosis.
Alias Symbols: DED, CHE1, CHE-1
Protein Interaction Partner: MDM2, DAPK3, AR, HIPK2, NGDN, UBC, TSG101, LIN28A, MMS19, ZNF468, NEDD4L, WHSC1, SMAD3, EFNB3, CPD, UBD, CAND1, PIN1, SIRT7, SUMO2, CHEK2, RELA, tat, MAGED1, PCBD2, SS18L1, LZTR1, MPHOSPH6, POLR2J, MPP6, PAWR, DAZAP2, ATR, ATM, CHEK1, LDOC1, SP1, RB1, MAP
Protein Size: 560 - 分子量
- 63 kDa
- 基因ID
- 26574
- NCBI登录号
- NM_012138, NP_036270
- UniProt
- Q9NY61
- 途径
- Neurotrophin Signaling Pathway, SARS-CoV-2 Protein Interactome
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