XRCC6 抗体 (N-Term)
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- 抗原 See all XRCC6 抗体
- XRCC6 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 (XRCC6))
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抗原表位
- N-Term
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适用
- 人, Cow
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This XRCC6 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- MSGWESYYKT EGDEEAEEEQ EENLEASGDY KYSGRDSLIF LVDASKAMFE
- 预测反应
- Cow: 79%, Human: 100%
- 产品特性
- This is a rabbit polyclonal antibody against G22P1. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Protein A purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human G22P1
- Top Product
- Discover our top product XRCC6 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 609 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- XRCC6 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 (XRCC6))
- 别名
- G22P1 (XRCC6 产品)
- 别名
- CTC75 antibody, CTCBF antibody, G22P1 antibody, KU70 antibody, ML8 antibody, TLAA antibody, 70kDa antibody, G22p1 antibody, Ku70 antibody, Kup70 antibody, X-ray repair cross complementing 6 antibody, ATP-dependent DNA helicase II, 70 kDa subunit antibody, X-ray repair complementing defective repair in Chinese hamster cells 6 L homeolog antibody, X-ray repair complementing defective repair in Chinese hamster cells 6 antibody, XRCC6 antibody, Bm1_41430 antibody, xrcc6.L antibody, Xrcc6 antibody
- 背景
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The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus.
Alias Symbols: ML8, KU70, TLAA, CTC75, CTCBF, G22P1
Protein Interaction Partner: UBC, ELF3, EHF, CHD1L, SUMO2, SUMO3, MDM2, EMD, ATRX, RPA3, RPA2, RPA1, PCNA, EED, PRPF40A, SUPT5H, ST13, SET, PLOD2, PIN1, NARS, MSH2, RPSA, JUP, IMPDH1, MSH6, GART, DPYSL3, CTNNA1, SAMHD1, ATP6V1B2, GANAB, SWAP70, WBP4, HYOU1, FARSB, RANBP3, CUL2, CSDE1
Protein Size: 609 - 分子量
- 70 kDa
- 基因ID
- 2547
- NCBI登录号
- NM_001469, NP_001460
- UniProt
- Q6FG89
- 途径
- DNA Damage Repair
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