PKC zeta 抗体 (N-Term)
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- 抗原 See all PKC zeta (PRKCZ) 抗体
- PKC zeta (PRKCZ) (Protein Kinase C, zeta (PRKCZ))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠, 兔, Cow, 犬, 马, 豚鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PKC zeta antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- MDSVMPSQEP PVDDKNEDAD LPSEETDGIA YISSSRKHDS IKDDSEDLKP
- 预测反应
- Cow: 77%, Dog: 75%, Guinea Pig: 75%, Horse: 75%, Human: 100%, Mouse: 92%, Rabbit: 79%, Rat: 92%
- 产品特性
- This is a rabbit polyclonal antibody against PRKCZ. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human PRKCZ
- Top Product
- Discover our top product PRKCZ Primary Antibody
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anti-Protein Kinase C, zeta (PRKCZ) (C-Term) antibody
PRKCZ 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, zeta (PRKCZ) (pThr410) antibodyPRKCZ 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, zeta (PRKCZ) (AA 165-255) antibodyPRKCZ 适用: 人 WB, ELISA, RNAi 宿主: 小鼠 Monoclonal 2D1 unconjugated
anti-Protein Kinase C, zeta (PRKCZ) (AA 453-592) antibodyPRKCZ 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, zeta (PRKCZ) (pThr560) antibodyPRKCZ 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, zeta (PRKCZ) (Cytoplasmic Domain) antibodyPRKCZ 适用: 人 ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, zeta (PRKCZ) (pThr410) antibodyPRKCZ 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, zeta (PRKCZ) (AA 220-231) antibodyPRKCZ 适用: 人, 小鼠, 大鼠 WB, ELISA, IP, ICC 宿主: 兔 Monoclonal R14-K unconjugated
anti-Protein Kinase C, zeta (PRKCZ) (Thr33) antibodyPRKCZ 适用: 人, 小鼠, 大鼠, 猴 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, zeta (PRKCZ) (pThr410) antibodyPRKCZ 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 409 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- PKC zeta (PRKCZ) (Protein Kinase C, zeta (PRKCZ))
- 别名
- PRKCZ (PRKCZ 产品)
- 别名
- TPKC antibody, PKCzeta antibody, prkcz-A antibody, pkc-zeta antibody, PRKCZ antibody, pkc2 antibody, PKC-ZETA antibody, PKC2 antibody, AI098070 antibody, C80388 antibody, Pkcz antibody, R74924 antibody, aPKCzeta antibody, zetaPKC antibody, 14-3-3-zetaisoform antibody, r14-3-3 antibody, pkcz antibody, si:ch211-150o23.4 antibody, protein kinase C zeta L homeolog antibody, protein kinase C zeta antibody, protein kinase C, zeta antibody, prkcz.L antibody, PRKCZ antibody, prkcz antibody, Prkcz antibody
- 背景
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Protein kinase C (PKC) zeta is a member of the PKC family of serine/threonine kinases which are involved in a variety of cellular processes such as proliferation, differentiation and secretion. Unlike the classical PKC isoenzymes which are calcium-dependent, PKC zeta exhibits a kinase activity which is independent of calcium and diacylglycerol but not of phosphatidylserine. Furthermore, it is insensitive to typical PKC inhibitors and cannot be activated by phorbol ester. Unlike the classical PKC isoenzymes, it has only a single zinc finger module. These structural and biochemical properties indicate that the zeta subspecies is related to, but distinct from other isoenzymes of PKC.Protein kinase C (PKC) zeta is a member of the PKC family of serine/threonine kinases which are involved in a variety of cellular processes such as proliferation, differentiation and secretion. Unlike the classical PKC isoenzymes which are calcium-dependent, PKC zeta exhibits a kinase activity which is independent of calcium and diacylglycerol but not of phosphatidylserine. Furthermore, it is insensitive to typical PKC inhibitors and cannot be activated by phorbol ester. Unlike the classical PKC isoenzymes, it has only a single zinc finger module. These structural and biochemical properties indicate that the zeta subspecies is related to, but distinct from other isoenzymes of PKC. Alternative splicing results in multiple transcript variants encoding different isoforms.
Alias Symbols: PKC2, PKC-ZETA
Protein Interaction Partner: MAPK7, PRKCZ, AKT2, AKT1, Sqstm1, PARD6A, NUMB, NPM1, HIST1H1B, CFL1, C1QBP, HSP90AA1, NCF1, MARCKS, PPP1R14A, HIST1H1A, UBC, VHL, LRRK2, AJUBA, PARD6B, PAWR, Smurf1, Smurf2, Pard3, HIST3H3, CD44, NCOA3, TFF1, RELA, ESR1, MBP, TRIM41, PIAS4, CCDC115, ZNF7
Protein Size: 409 - 分子量
- 45 kDa
- 基因ID
- 5590
- NCBI登录号
- NM_001033581, NP_001028753
- UniProt
- Q05513
- 途径
- NF-kappaB Signaling, RTK signaling, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Synaptic Membrane, Production of Molecular Mediator of Immune Response, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling
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