-
- 抗原 See all EGFR 抗体
- EGFR (Epidermal Growth Factor Receptor (EGFR))
-
适用
- 人
-
宿主
- 小鼠
-
克隆类型
- 单克隆
-
标记
- This EGFR antibody is un-conjugated
-
应用范围
- Flow Cytometry (FACS), Fluorescence Microscopy (FM)
- 品牌
- BD Pharmingen™
- 产品特性
-
Reacts with epidermal growth factor receptor (EGFR), a glycoprotein of approximately 170 kDa, expressed on most cells. It consists of a glycosylated extracellular domain which recognizes epidermal growth factor (EGF), a transmembrane domain, and an intracellular domain with tyrosine-kinase activity essential for signal transduction. EGFR plays an important role in the growth and differentiation of many cellular types. Transforming growth factor á(TGFα) and vaccinia virus growth factor also interact with EGFR. Profile of A431, an epidermoid carcinoma cell line, analyzed on a FACScan .
BD Pharmingen™ Purified Mouse Anti-Human EGF Receptor - Purified - Clone EGFR.1 - Isotype Mouse IgG2b, κ - Reactivity Hu - 0.1 mg - 纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
- 克隆位点
- EGFR-1
- 亚型
- IgG2b kappa
- Top Product
- Discover our top product EGFR Primary Antibody
-
-
- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
-
- 浓度
- 0.5 mg/mL
- 缓冲液
- Aqueous buffered solution containing ≤0.09 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Store undiluted at 4°C.
-
-
Demonstration of epidermal growth factor receptor in colorectal adenocarcinoma by enzyme immunoassay." in: Digestion, Vol. 55, Issue 2, pp. 103-7, (1994) (PubMed).
: "A new monoclonal antibody for detection of EGF-receptors in western blots and paraffin-embedded tissue sections." in: Journal of cellular biochemistry, Vol. 49, Issue 2, pp. 157-65, (1992) (PubMed).
: "
-
Demonstration of epidermal growth factor receptor in colorectal adenocarcinoma by enzyme immunoassay." in: Digestion, Vol. 55, Issue 2, pp. 103-7, (1994) (PubMed).
-
- 抗原
- EGFR (Epidermal Growth Factor Receptor (EGFR))
- 别名
- EGF Receptor (EGFR 产品)
- 别名
- C-erb antibody, CG10079 antibody, D-EGFR antibody, D-Egf antibody, DEGFR antibody, DER antibody, DER flb antibody, DER/EGFR antibody, DER/faint little ball antibody, DER/top antibody, DER/torpedo antibody, DER1 antibody, DEgfr antibody, Degfr antibody, Der antibody, DmHD-33 antibody, Dmel\\CG10079 antibody, EFG-R antibody, EGF-R antibody, EGFR antibody, EGFr antibody, EGfr antibody, EK2-6 antibody, Egf antibody, Egf-r antibody, EgfR antibody, El antibody, Elp antibody, Elp-1 antibody, Elp-B1 antibody, Elp-B1RB1 antibody, HD-33 antibody, TOP antibody, Torpedo/DER antibody, Torpedo/Egfr antibody, c-erbB antibody, d-egf-r antibody, dEGFR antibody, dEGFR1 antibody, dEgfr antibody, der antibody, egfr antibody, flb antibody, l(2)05351 antibody, l(2)09261 antibody, l(2)57DEFa antibody, l(2)57EFa antibody, l(2)57Ea antibody, mor1 antibody, top antibody, top/DER antibody, top/flb antibody, torpedo/Egfr antibody, torpedo/egfr antibody, EGFR12 antibody, EGFR15 antibody, egfr1 antibody, Erbb2 antibody, ERBB antibody, ERBB1 antibody, HER1 antibody, PIG61 antibody, mENA antibody, ErbB-1 antibody, Errp antibody, 9030024J15Rik antibody, AI552599 antibody, Erbb antibody, Errb1 antibody, Wa5 antibody, wa-2 antibody, wa2 antibody, epidermal growth factor receptor antibody, Epidermal growth factor receptor antibody, epidermal growth factor receptor a (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian) antibody, EGFR antibody, Egfr antibody, egfra antibody, egfr1 antibody, LOC5564544 antibody
- 途径
- NF-kappaB Signaling, RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Stem Cell Maintenance, Hepatitis C, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, EGFR Downregulation, S100 Proteins
-