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CD42a 抗体

GP9 适用: 人 FACS 宿主: 小鼠 Monoclonal ALMA-16 unconjugated
产品编号 ABIN2689252
发货至: 中国
  • 抗原 See all CD42a (GP9) 抗体
    CD42a (GP9) (Glycoprotein IX (Platelet) (GP9))
    适用
    • 61
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    宿主
    • 41
    • 23
    小鼠
    克隆类型
    • 43
    • 21
    单克隆
    标记
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    This CD42a antibody is un-conjugated
    应用范围
    • 26
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    Flow Cytometry (FACS)
    品牌
    BD Pharmingen™
    产品特性
    Reacts with a 17-22kD, single chain integral membrane glycoprotein, also known as GPIX. CD42a forms a noncovalently linked complex (GPIb/GPIX/GPV) with CD42b, CD42c and CD42d. It is expressed on platelets and megakaryocytes and is absent on the platelets of patients with Bernadr-Soulier Syndrome (BSS). Although the CD42a function is not fully understood, GPIX glycoprotein is important for the assembly and membrane expression of the complex and for the maintenance of the functional conformation of CD42b (GPIb). Profile of resting platelets analyzed by flow cytometry

    BD Pharmingen™ Purified Mouse Anti-Human CD42a - Purified - Clone ALMA.16 - Isotype Mouse IgG1, κ - Reactivity Hu - 0.1 mg
    纯化方法
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    克隆位点
    ALMA-16
    亚型
    IgG1 kappa
    Top Product
    Discover our top product GP9 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Aqueous buffered solution containing ≤0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store undiluted at 4°C.
  • Schick, Walker: "The acylation of megakaryocyte proteins: glycoprotein IX is primarily myristoylated while glycoprotein Ib is palmitoylated." in: Blood, Vol. 87, Issue 4, pp. 1377-84, (1996) (PubMed).

    Hickey, Williams, Roth: "Human platelet glycoprotein IX: an adhesive prototype of leucine-rich glycoproteins with flank-center-flank structures." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 86, Issue 17, pp. 6773-7, (1989) (PubMed).

    Fox, Aggerbeck, Berndt: "Structure of the glycoprotein Ib.IX complex from platelet membranes." in: The Journal of biological chemistry, Vol. 263, Issue 10, pp. 4882-90, (1988) (PubMed).

  • 抗原
    CD42a (GP9) (Glycoprotein IX (Platelet) (GP9))
    别名
    CD42a (GP9 产品)
    别名
    cd42a antibody, gpix antibody, GP9 antibody, GPIX antibody, Cd42 antibody, CD42a antibody, glycoprotein IX platelet antibody, glycoprotein IX platelet L homeolog antibody, glycoprotein IX (platelet) antibody, glycoprotein 9 (platelet) antibody, GP9 antibody, gp9.L antibody, Gp9 antibody
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