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CD42a 产品

(Glycoprotein IX (Platelet) (GP9))

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This gene encodes a small membrane glycoprotein found on the surface of human platelets. It forms a 1-to-1 noncovalent complex with glycoprotein Ib, a platelet surface membrane glycoprotein complex that functions as a receptor for von Willebrand factor. The complete receptor complex includes noncovalent association of the alpha and beta subunits with the protein encoded by this gene and platelet glycoprotein V. Defects in this gene are a cause of Bernard-Soulier syndrome, also known as giant platelet disease. These patients have unusually large platelets and have a clinical bleeding tendency. [provided by RefSeq, Oct 2008].

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Featured CD42a Categories

CD42a 抗体

High quality antibodies with extensive validation data.

CD42a ELISA试剂盒

Reliable ELISA kits for a wide range of species.

CD42a 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended CD42a 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Rat
Application WB, IHC, IP, ICC
Validations
  • (6)
Cat. No. ABIN7442297
Quantity 100 μL
Datasheet Datasheet
Reactivity Dog, Human
Application FACS
Validations
  • (3)
  • (3)
Cat. No. ABIN1981888
Quantity 100 tests
Datasheet Datasheet
Reactivity Human
Application WB, FACS, IHC, ELISA, ICC, Neut
Validations
  • (4)
Cat. No. ABIN7193213
Quantity 0.1 mg
Datasheet Datasheet

Recommended CD42a ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN5591815
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN1148314
Quantity 96 tests
Datasheet Datasheet

Recommended CD42a 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN7274762
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1355503
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1355501
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our CD42a Products

Din, Aftab, Jubb, Carnegy, Lyall, Sarma, Newby, Flapan: "Effect of moderate walnut consumption on lipid profile, arterial stiffness and platelet activation in humans." in: European journal of clinical nutrition, Vol. 65, Issue 2, pp. 234-9, (2011) (PubMed).

Bournazos, Rennie, Hart, Fox, Dransfield: "Monocyte functional responsiveness after PSGL-1-mediated platelet adhesion is dependent on platelet activation status." in: Arteriosclerosis, thrombosis, and vascular biology, Vol. 28, Issue 8, pp. 1491-8, (2008) (PubMed).

Aasted, Viuff: "Reactivity of monoclonal antibodies to human CD antigens with cells from mink." in: Veterinary immunology and immunopathology, Vol. 119, Issue 1-2, pp. 27-37, (2007) (PubMed).

Harding, Din, Sarma, Josephs, Fox, Newby: "Promotion of proinflammatory interactions between platelets and monocytes by unfractionated heparin." in: Heart (British Cardiac Society), Vol. 92, Issue 11, pp. 1635-8, (2006) (PubMed).

Sarma, Laan, Alam, Jha, Fox, Dransfield: "Increased platelet binding to circulating monocytes in acute coronary syndromes." in: Circulation, Vol. 105, Issue 18, pp. 2166-71, (2002) (PubMed).

Brown, Clarke, Magowan, Sanderson, Savill: "Constitutive death of platelets leading to scavenger receptor-mediated phagocytosis. A caspase-independent cell clearance program." in: The Journal of biological chemistry, Vol. 275, Issue 8, pp. 5987-96, (2000) (PubMed).

Schick, Walker: "The acylation of megakaryocyte proteins: glycoprotein IX is primarily myristoylated while glycoprotein Ib is palmitoylated." in: Blood, Vol. 87, Issue 4, pp. 1377-84, (1996) (PubMed).

Hickey, Williams, Roth: "Human platelet glycoprotein IX: an adhesive prototype of leucine-rich glycoproteins with flank-center-flank structures." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 86, Issue 17, pp. 6773-7, (1989) (PubMed).

Synonyms and alternative names related to CD42a

glycoprotein IX platelet (GP9), glycoprotein IX platelet L homeolog (gp9.L), glycoprotein IX (platelet) (Gp9), glycoprotein 9 (platelet) (Gp9), Cd42, cd42a, CD42a, GP9, gpix, GPIX

Protein level used designations for CD42a

  • glycoprotein IX (platelet)
  • glycoprotein 9 (platelet)
  • platelet glycoprotein IX
  • GP-IX
  • glycoprotein 9
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