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(CD4)
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This gene encodes a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigenes and is also a receptor for the human immunodeficiency virus. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq, Aug 2010].
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Featured CD4 Categories
CD4 抗体
High quality antibodies with extensive validation data.
CD4 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
CD4 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended CD4 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Chicken, Human, Mouse, Pig, Rat
Application
FACS, WB, ELISA, IHC (fro), IHC (p), IF (cc), IF (p)
Validations
- (4)
- (7)
- (1)
Cat. No.
ABIN671376
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Avian, Cat, Chicken, Cow, Dog, Donkey, Goat, Guinea Pig, Hamster, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat, Sheep
Application
WB
Validations
- (1)
- (6)
Cat. No.
ABIN6254232
Quantity
600 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
FACS, WB, ELISA, IHC (fro), IHC (p), IF (cc), IF (p)
Validations
- (8)
- (5)
Cat. No.
ABIN672936
Quantity
100 μL
Datasheet
Datasheet
Recommended CD4 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (5)
Cat. No.
ABIN6730914
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Chicken
Analytical Method
Quantitative Competition ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6975282
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6965574
Quantity
96 tests
Datasheet
Datasheet
Recommended CD4 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (4)
Cat. No.
ABIN7274184
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (3)
Cat. No.
ABIN7274181
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Rhesus Monkey
Source
HEK-293 Cells
Validations
- (3)
Cat. No.
ABIN7274190
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our CD4 Products
: "Inhibition of DNM1L and mitochondrial fission attenuates inflammatory response in fibroblast-like synoviocytes of rheumatoid arthritis." in: Journal of cellular and molecular medicine, Vol. 24, Issue 2, pp. 1516-1528, (2021) (PubMed).: "Parenteral vaccination protects against transcervical infection with Chlamydia trachomatis and generate tissue-resident T cells post-challenge." in: NPJ vaccines, Vol. 5, pp. 7, (2020) (PubMed).
: "MEK inhibition suppresses B regulatory cells and augments anti-tumor immunity." in: PLoS ONE, Vol. 14, Issue 10, pp. e0224600, (2020) (PubMed).
: "Immune Response to Salmonella Enteritidis Infection in Broilers Immunized Orally With Chitosan-Based Salmonella Subunit Nanoparticle Vaccine." in: Frontiers in immunology, Vol. 11, pp. 935, (2020) (PubMed).
: "Adjuvant Postoperative CD40 Agonist and PD-1 Antagonist Combination Therapy in Syngeneic Tongue Cancer Mouse Model." in: Anticancer research, Vol. 40, Issue 5, pp. 2707-2713, (2020) (PubMed).
: "A Serotonin-Modulated Circuit Controls Sleep Architecture to Regulate Cognitive Function Independent of Total Sleep in Drosophila." in: Current biology : CB, Vol. 29, Issue 21, pp. 3635-3646.e5, (2019) (PubMed).
: "High fat diet downregulates regulatory T cells in the myocardium of spontaneous hypertensive rats." in: Nutrition, metabolism, and cardiovascular diseases : NMCD, Vol. 29, Issue 11, pp. 1254-1260, (2019) (PubMed).
: "Trafficking of immune cells across the blood-brain barrier is modulated by neurofibrillary pathology in tauopathies." in: PLoS ONE, Vol. 14, Issue 5, pp. e0217216, (2019) (PubMed).
: "ER��-selective agonist alleviates inflammation in a multiple sclerosis model via regulation of MHC II in microglia." in: American journal of translational research, Vol. 11, Issue 7, pp. 4411-4424, (2019) (PubMed).
: "Age-Related Dopaminergic Innervation Augments T Helper 2-Type Allergic Inflammation in the Postnatal Lung." in: Immunity, Vol. 51, Issue 6, pp. 1102-1118.e7, (2019) (PubMed).
Synonyms and alternative names related to CD4
CD4 molecule (CD4), carcinoembryonic antigen-related cell adhesion molecule 5 (LOC100125525), T-cell surface glycoprotein CD4 (cd4), CD4 antigen (Cd4), Cd4 molecule (Cd4), CD4 molecule (Cd4), cd4, CD4mut, L3T4, Ly-4, p55, W3/25Protein level used designations for CD4
- CD4 antigen
- T-cell surface glycoprotein CD4
- T-cell differentiation antigen L3T4
- T-cell surface antigen T4/Leu-3
- T-cell surface glycoprotein CD4 precursor (T-cell surface antigen T4/Leu-3) (T-cell differentiation antigen L3T4)
- CD4 antigen (p55)
- CD4 receptor
- W3/25 antigen
- lymphocyte antigen CD4
- cell surface glycoprotein CD4
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