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ICOSLG 抗体

ICOSLG 适用: 人 FACS 宿主: 小鼠 Monoclonal 2D3-B7 unconjugated
产品编号 ABIN2689136
发货至: 中国
  • 抗原 See all ICOSLG 抗体
    ICOSLG (Inducible T-Cell Co-Stimulator Ligand (ICOSLG))
    适用
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    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This ICOSLG antibody is un-conjugated
    应用范围
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    Flow Cytometry (FACS)
    品牌
    BD Pharmingen™
    产品特性
    Reacts with a 302 amino acid cell surface protein termed B7-H2 (B-7 homologue 2). B7-H2 binds to a CD28-like receptor inducible costimulator (ICOS) and costimulates the proliferation and cytokine production of human T cells. It is weakly expressed on peripheral blood mononuclear cells, but it is expressed on monocyte-derived dendritic cells. This antibody could be useful in the study of dendritic cell development and/or costimulatory molecules. This antibody is routinely tested by flow cytometric analysis. Other applications were tested during antibody development only or reported in the literature. Profile of B7-H2 (2D3/B7-H2) expression on CHO-B7-H2 cells analyzed by flow cytometry. Second step staining with Cat. No. 555988.

    BD Pharmingen™ Purified Mouse Anti-Human CD275 - Purified - Clone 2D3/B7-H2 - Isotype Mouse IgG2b, κ - Reactivity Hu - 0.1 mg
    纯化方法
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    克隆位点
    2D3-B7
    亚型
    IgG2b kappa
    Top Product
    Discover our top product ICOSLG Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Aqueous buffered solution containing ≤0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store undiluted at 4°C.
  • Wang, Zhu, Chapoval, Dong, Tamada, Ni, Chen: "Costimulation of T cells by B7-H2, a B7-like molecule that binds ICOS." in: Blood, Vol. 96, Issue 8, pp. 2808-13, (2000) (PubMed).

    Bretscher: "A two-step, two-signal model for the primary activation of precursor helper T cells." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 96, Issue 1, pp. 185-90, (1999) (PubMed).

    Dong, Zhu, Tamada, Chen: "B7-H1, a third member of the B7 family, co-stimulates T-cell proliferation and interleukin-10 secretion." in: Nature medicine, Vol. 5, Issue 12, pp. 1365-9, (1999) (PubMed).

  • 抗原
    ICOSLG (Inducible T-Cell Co-Stimulator Ligand (ICOSLG))
    别名
    CD275 (ICOSLG 产品)
    别名
    ICOSLG antibody, AU044799 antibody, B7-H2 antibody, B7RP-1 antibody, B7h antibody, BG071784 antibody, GI50 antibody, GL50 antibody, GL50-B antibody, ICOS-L antibody, Icoslg antibody, LICOS antibody, Ly115l antibody, mKIAA0653 antibody, B7H2 antibody, B7RP1 antibody, CD275 antibody, ICOSL antibody, Icosl antibody, RGD1562791 antibody, inducible T-cell costimulator ligand antibody, icos ligand antibody, inducible T-cell co-stimulator ligand antibody, ICOSLG antibody, Icosl antibody, Icoslg antibody
    背景
    Synonyms: B7-H2
    途径
    Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation
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