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- 抗原 See all ICOSLG 抗体
- ICOSLG (Inducible T-Cell Co-Stimulator Ligand (ICOSLG))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This ICOSLG antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS)
- 品牌
- BD Pharmingen™
- 产品特性
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Reacts with a 302 amino acid cell surface protein termed B7-H2 (B-7 homologue 2). B7-H2 binds to a CD28-like receptor inducible costimulator (ICOS) and costimulates the proliferation and cytokine production of human T cells. It is weakly expressed on peripheral blood mononuclear cells, but it is expressed on monocyte-derived dendritic cells. This antibody could be useful in the study of dendritic cell development and/or costimulatory molecules. This antibody is routinely tested by flow cytometric analysis. Other applications were tested during antibody development only or reported in the literature. Profile of B7-H2 (2D3/B7-H2) expression on CHO-B7-H2 cells analyzed by flow cytometry. Second step staining with Cat. No. 555988.
BD Pharmingen™ Purified Mouse Anti-Human CD275 - Purified - Clone 2D3/B7-H2 - Isotype Mouse IgG2b, κ - Reactivity Hu - 0.1 mg - 纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
- 克隆位点
- 2D3-B7
- 亚型
- IgG2b kappa
- Top Product
- Discover our top product ICOSLG Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 浓度
- 0.5 mg/mL
- 缓冲液
- Aqueous buffered solution containing ≤0.09 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Store undiluted at 4°C.
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Costimulation of T cells by B7-H2, a B7-like molecule that binds ICOS." in: Blood, Vol. 96, Issue 8, pp. 2808-13, (2000) (PubMed).
: "A two-step, two-signal model for the primary activation of precursor helper T cells." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 96, Issue 1, pp. 185-90, (1999) (PubMed).
: "B7-H1, a third member of the B7 family, co-stimulates T-cell proliferation and interleukin-10 secretion." in: Nature medicine, Vol. 5, Issue 12, pp. 1365-9, (1999) (PubMed).
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Costimulation of T cells by B7-H2, a B7-like molecule that binds ICOS." in: Blood, Vol. 96, Issue 8, pp. 2808-13, (2000) (PubMed).
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- 抗原
- ICOSLG (Inducible T-Cell Co-Stimulator Ligand (ICOSLG))
- 别名
- CD275 (ICOSLG 产品)
- 别名
- ICOSLG antibody, AU044799 antibody, B7-H2 antibody, B7RP-1 antibody, B7h antibody, BG071784 antibody, GI50 antibody, GL50 antibody, GL50-B antibody, ICOS-L antibody, Icoslg antibody, LICOS antibody, Ly115l antibody, mKIAA0653 antibody, B7H2 antibody, B7RP1 antibody, CD275 antibody, ICOSL antibody, Icosl antibody, RGD1562791 antibody, inducible T-cell costimulator ligand antibody, icos ligand antibody, inducible T-cell co-stimulator ligand antibody, ICOSLG antibody, Icosl antibody, Icoslg antibody
- 背景
- Synonyms: B7-H2
- 途径
- Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation
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