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- 抗原 See all FGFR4 抗体
- FGFR4 (Fibroblast Growth Factor Receptor 4 (FGFR4))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This FGFR4 antibody is conjugated to PE
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应用范围
- ELISA
- 产品特性
- The 4FR6D3 antibody recognizes human CD334, also known as fibroblast growth factor 4, FGFR4 and TKF. CD334 is a member of the fibroblast growth factor receptor family and a cell surface tyrosine kinase containing three immunoglobulin-like domains. FGFR4 has a predicted molecular weight of approximately 88 kD and is widely expressed in many tissues including the intestine, muscle, heart, cornea, retina, and pancreas, with highest expression in lung and kidney.CD334 binds acidic fibroblast growth factors (FGF8, GFG1, FGF19, FGF6, and FGF2), ligand binding induces mitogenesis and differentiation. CD334 has been shown to interact with STAT1 and STAT3 and is over-expressed in gynecological tumors suggesting a possible role for this receptor in breast and ovarian tumorigenesis. Unique alleles (Arg388) in FGFR4 have been shown to be associated with cancer progression and increased tumor cell motility. The 4FR6D3 antibody has been shown to be useful for flow cytometry.
- 纯化方法
- The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.
- 克隆位点
- 4FR6D3
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product FGFR4 Primary Antibody
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anti-Fibroblast Growth Factor Receptor 4 (FGFR4) (AA 22-369) antibody
FGFR4 适用: 人, 猴 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 8A1G2 unconjugated
anti-Fibroblast Growth Factor Receptor 4 (FGFR4) (AA 22-369) antibodyFGFR4 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 3B5B8 unconjugated
anti-Fibroblast Growth Factor Receptor 4 (FGFR4) (AA 24-55), (N-Term) antibodyFGFR4 适用: 人, 小鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB38171 unconjugated
anti-Fibroblast Growth Factor Receptor 4 (FGFR4) (AA 24-55) antibodyFGFR4 适用: 人 WB, ELISA, IHC, FACS, IF 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor Receptor 4 (FGFR4) (AA 31-145) antibodyFGFR4 适用: 人 WB, ELISA, PLA 宿主: 小鼠 Monoclonal 1E2 unconjugated
anti-Fibroblast Growth Factor Receptor 4 (FGFR4) antibodyFGFR4 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Fibroblast Growth Factor Receptor 4 (FGFR4) antibodyFGFR4 适用: 人 WB, ELISA, IHC 宿主: 小鼠 Monoclonal 4H2B10B2 unconjugated
anti-Fibroblast Growth Factor Receptor 4 (FGFR4) (AA 1-100) antibodyFGFR4 适用: 人, 大鼠 ELISA, IHC (p), IF (cc), IF (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor Receptor 4 (FGFR4) (AA 168-369) antibodyFGFR4 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor Receptor 4 (FGFR4) (AA 25-182) antibodyFGFR4 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 缓冲液
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Protect from prolonged exposure to light. Do not freeze.
- 储存条件
- 4 °C
- 储存方法
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- 抗原
- FGFR4 (Fibroblast Growth Factor Receptor 4 (FGFR4))
- 别名
- CD334 (FGFR4 产品)
- 别名
- FGFR4 antibody, XFGFR-4 antibody, XFGFR-4a antibody, cd334 antibody, fgfr-4 antibody, jtk2 antibody, tkf antibody, xfgfr4 antibody, CD334 antibody, JTK2 antibody, TKF antibody, Fgfr-4 antibody, etID309818.21 antibody, wu:fc13h10 antibody, zgc:111935 antibody, fgfr-4c antibody, fgfr4 antibody, fibroblast growth factor receptor 4 antibody, fibroblast growth factor receptor 4 S homeolog antibody, FGFR4 antibody, fgfr4 antibody, Fgfr4 antibody, fgfr4.S antibody
- 途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis, Growth Factor Binding
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