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IGF1R 抗体 (pTyr1346)
IGF1R
适用: 人, 小鼠, 大鼠
IHC
宿主: 兔
Polyclonal
unconjugated
IGF1R抗体详情
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抗原
See all IGF1R 抗体
IGF1R
(Insulin-Like Growth Factor 1 Receptor (IGF1R))
抗原表位
All epitopes for IGF1R 抗体
pTyr1346
适用
All reactivities for IGF1R 抗体
人, 小鼠, 大鼠
宿主
All hosts for IGF1R 抗体
兔
克隆类型
All clonalities for IGF1R 抗体
多克隆
标记
All conjugates for IGF1R 抗体
This IGF1R antibody is un-conjugated
应用范围
All applications for IGF1R 抗体
Immunohistochemistry (IHC)
特异性
The antibody detects endogenous levels of IGF1R only when phosphorylated at tyrosine 1346.
纯化方法
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
免疫原
IGF1R (phospho Tyr1346) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 1346 (Q-P-Y (p)-A-H) derived from Human IGF1R .
亚型
IgG
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Alternatives
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使用细节
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应用备注
Optimal working dilution should be determined by the investigator.
限制
仅限研究用
贮存及处理
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状态
Liquid
浓度
1 mg/mL
缓冲液
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
-20 °C
储存方法
Store antibody at -20°C for up to one year.
IGF1R目标详情
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抗原
IGF1R
(Insulin-Like Growth Factor 1 Receptor (IGF1R))
别名
IGF1R (IGF1R 产品 )
别名
CMT2N antibody, CD221 antibody, IGFIR antibody, IGFR antibody, JTK13 antibody, IGFIRC antibody, IGFR1 antibody, IGF-1R antibody, IGF1R antibody, DKFZp469I0618 antibody, igf-1r antibody, xIGF-1R antibody, xIGFR antibody, xigf1r antibody, A330103N21Rik antibody, D930020L01 antibody, hyft antibody, igf-ir antibody, IGF-IR antibody, IGF-IRb antibody, wu:fb03h06 antibody, IGF-IRa antibody, sb:eu1090 antibody, wu:fi20b10 antibody, alanyl-tRNA synthetase antibody, insulin like growth factor 1 receptor antibody, insulin-like growth factor 1 receptor antibody, insulin-like growth factor 1 antibody, insulin-like growth factor I receptor antibody, insulin like growth factor 1 receptor S homeolog antibody, insulin-like growth factor 1b receptor antibody, insulin-like growth factor 1a receptor antibody, AARS antibody, IGF1R antibody, Igf1r antibody, igf1r antibody, Igf1 antibody, LOC780503 antibody, LOC100136427 antibody, igf1r.S antibody, igf1rb antibody, igf1ra antibody
背景
This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival.
分子量
154 kDa
基因ID
3480
NCBI登录号
NP_000866
UniProt
P08069
途径
RTK signaling , Regulation of Hormone Metabolic Process , Regulation of Hormone Biosynthetic Process , Autophagy
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