FANCD2 抗体 (pSer222)
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- 抗原 See all FANCD2 抗体
- FANCD2 (Fanconi Anemia, Complementation Group D2 (FANCD2))
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抗原表位
- pSer222
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This FANCD2 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 特异性
- The antibody detects endogenous level of FANCD2 only when phosphorylated at serine 222.
- 纯化方法
- Antibodies were purified by affinity-chromatography using epitope-specific peptide.
- 免疫原
- FANCD2 (phospho Ser222) antibody was raised against a peptide sequence around phosphorylation site of serine 222 (G-D-S (p)-Q-H) derived from Human FANCD2.
- 亚型
- IgG
- Top Product
- Discover our top product FANCD2 Primary Antibody
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anti-Fanconi Anemia, Complementation Group D2 (FANCD2) (N-Term) antibody
FANCD2 适用: 人, 小鼠 WB, IHC, IF, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Fanconi Anemia, Complementation Group D2 (FANCD2) (AA 1-230) antibodyFANCD2 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Fanconi Anemia, Complementation Group D2 (FANCD2) (N-Term) antibodyFANCD2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Fanconi Anemia, Complementation Group D2 (FANCD2) (pSer222) antibodyFANCD2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Fanconi Anemia, Complementation Group D2 (FANCD2) (AA 1-291) antibodyFANCD2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Fanconi Anemia, Complementation Group D2 (FANCD2) antibodyFANCD2 适用: 人 IF 宿主: 兔 Polyclonal unconjugated
anti-Fanconi Anemia, Complementation Group D2 (FANCD2) antibodyFANCD2 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-Fanconi Anemia, Complementation Group D2 (FANCD2) (pSer222) antibodyFANCD2 适用: 人 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Fanconi Anemia, Complementation Group D2 (FANCD2) (AA 893-927) antibodyFANCD2 适用: 人 WB 宿主: 兔 Polyclonal RB49367 unconjugated
anti-Fanconi Anemia, Complementation Group D2 (FANCD2) antibodyKO Validated FANCD2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Western Blot: 1:500~1:1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store antibody at -20°C for up to one year.
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- 抗原
- FANCD2 (Fanconi Anemia, Complementation Group D2 (FANCD2))
- 别名
- FANCD2 (FANCD2 产品)
- 别名
- FANCD2 antibody, CG17269 antibody, CG31192 antibody, CG31194 antibody, Dmel\\CG17269 antibody, dmFANCD2 antibody, xfancd2 antibody, FA-D2 antibody, FA4 antibody, FACD antibody, FAD antibody, FAD2 antibody, FANCD antibody, 2410150O07Rik antibody, AU015151 antibody, BB137857 antibody, Fanconi anemia complementation group D2 antibody, CG17269 gene product from transcript CG17269-RA antibody, Fanconi anemia group D2 protein antibody, Fanconi anemia, complementation group D2 antibody, Fanconi anemia complementation group D2 L homeolog antibody, FANCD2 antibody, Fancd2 antibody, LOC100455970 antibody, fancd2 antibody, fancd2.L antibody
- 背景
- Required for maintenance of chromosomal stability. Promotes accurate and efficient pairing of homologs during meiosis. Involved in the repair of DNA double-strand breaks, both by homologous recombination and single-strand annealing. May participate in S phase and G2 phase checkpoint activation upon DNA damage. Plays a role in preventing breakage and loss of missegregating chromatin at the end of cell division, particularly after replication stress. Required for the targeting, or stabilization, of BLM to non-centromeric abnormal structures induced by replicative stress. Promotes BRCA2/FANCD1 loading onto damaged chromatin. May also be involved in B-cell immunoglobulin isotype switching.
- 分子量
- 166 kDa
- 基因ID
- 2177
- NCBI登录号
- NP_001018125
- UniProt
- Q9BXW9
- 途径
- DNA Damage Repair
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