FANCD2 抗体
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- 抗原 See all FANCD2 抗体
- FANCD2 (Fanconi Anemia, Complementation Group D2 (FANCD2))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This FANCD2 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 特异性
- This antibody ist KO validated.
- 产品特性
- Polyclonal Antibody
- 纯化方法
- Affinity purification
- 质量等级
- KO Validated
- 免疫原
- Recombinant fusion protein of human FANCD2 (NP_149075.2).
- 亚型
- IgG
- Top Product
- Discover our top product FANCD2 Primary Antibody
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- 应用备注
- WB 1:500-1:2000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- FANCD2 (Fanconi Anemia, Complementation Group D2 (FANCD2))
- 别名
- FANCD2 (FANCD2 产品)
- 别名
- FANCD2 antibody, CG17269 antibody, CG31192 antibody, CG31194 antibody, Dmel\\CG17269 antibody, dmFANCD2 antibody, xfancd2 antibody, FA-D2 antibody, FA4 antibody, FACD antibody, FAD antibody, FAD2 antibody, FANCD antibody, 2410150O07Rik antibody, AU015151 antibody, BB137857 antibody, Fanconi anemia complementation group D2 antibody, CG17269 gene product from transcript CG17269-RA antibody, Fanconi anemia group D2 protein antibody, Fanconi anemia, complementation group D2 antibody, Fanconi anemia complementation group D2 L homeolog antibody, FANCD2 antibody, Fancd2 antibody, LOC100455970 antibody, fancd2 antibody, fancd2.L antibody
- 背景
- The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity, they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group D2. This protein is monoubiquinated in response to DNA damage, resulting in its localization to nuclear foci with other proteins (BRCA1 AND BRCA2) involved in homology-directed DNA repair. Alternative splicing results in multiple transcript variants.
- 分子量
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Observed_MW: 166 kDa
Calculated_MW: 27 kDa/140 kDa/164 kDa/166 kDa
- 基因ID
- 2177
- UniProt
- Q9BXW9
- 途径
- DNA Damage Repair
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