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FANCD2 抗体 (N-Term)

FANCD2 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6261674
发货至: 中国
  • 抗原 See all FANCD2 抗体
    FANCD2 (Fanconi Anemia, Complementation Group D2 (FANCD2))
    抗原表位
    • 16
    • 15
    • 15
    • 8
    • 7
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 101
    • 24
    • 21
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 100
    • 2
    克隆类型
    • 90
    • 12
    多克隆
    标记
    • 34
    • 8
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This FANCD2 antibody is un-conjugated
    应用范围
    • 28
    • 27
    • 27
    • 23
    • 15
    • 14
    • 12
    • 8
    • 8
    • 7
    • 5
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    特异性
    FANCD2 Antibody detects endogenous levels of total FANCD2.
    预测反应
    Pig,Bovine,Horse,Sheep,Rabbit,Dog,Xenopus
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human FANCD2, corresponding to a region within N-terminal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product FANCD2 Primary Antibody
  • 应用备注
    WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    FANCD2 (Fanconi Anemia, Complementation Group D2 (FANCD2))
    别名
    FANCD2 (FANCD2 产品)
    别名
    FANCD2 antibody, CG17269 antibody, CG31192 antibody, CG31194 antibody, Dmel\\CG17269 antibody, dmFANCD2 antibody, xfancd2 antibody, FA-D2 antibody, FA4 antibody, FACD antibody, FAD antibody, FAD2 antibody, FANCD antibody, 2410150O07Rik antibody, AU015151 antibody, BB137857 antibody, Fanconi anemia complementation group D2 antibody, CG17269 gene product from transcript CG17269-RA antibody, Fanconi anemia group D2 protein antibody, Fanconi anemia, complementation group D2 antibody, Fanconi anemia complementation group D2 L homeolog antibody, FANCD2 antibody, Fancd2 antibody, LOC100455970 antibody, fancd2 antibody, fancd2.L antibody
    背景

    Description: Required for maintenance of chromosomal stability. Promotes accurate and efficient pairing of homologs during meiosis. Involved in the repair of DNA double-strand breaks, both by homologous recombination and single-strand annealing. May participate in S phase and G2 phase checkpoint activation upon DNA damage. Plays a role in preventing breakage and loss of missegregating chromatin at the end of cell division, particularly after replication stress. Required for the targeting, or stabilization, of BLM to non-centromeric abnormal structures induced by replicative stress. Promotes BRCA2/FANCD1 loading onto damaged chromatin. May also be involved in B-cell immunoglobulin isotype switching.

    Gene: FANCD2

    分子量
    166kDa
    基因ID
    2177
    UniProt
    Q9BXW9
    途径
    DNA Damage Repair
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