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FAS 抗体 (AA 21-165)

FAS 适用: 人, 大鼠, 小鼠 WB 宿主: 小鸡 Polyclonal unconjugated
产品编号 ABIN2467815
发货至: 中国
  • 抗原 See all FAS 抗体
    FAS (TNF Receptor Superfamily, Member 6 (FAS))
    抗原表位
    • 25
    • 16
    • 16
    • 8
    • 7
    • 6
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 21-165
    适用
    • 207
    • 65
    • 61
    • 19
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    人, 大鼠, 小鼠
    宿主
    • 156
    • 86
    • 4
    • 2
    • 1
    • 1
    小鸡
    克隆类型
    • 155
    • 93
    • 1
    多克隆
    标记
    • 115
    • 27
    • 25
    • 12
    • 11
    • 7
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FAS antibody is un-conjugated
    应用范围
    • 159
    • 113
    • 73
    • 64
    • 35
    • 33
    • 27
    • 26
    • 26
    • 18
    • 16
    • 9
    • 8
    • 6
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    纯化方法
    Antigen affinity-purified
    Top Product
    Discover our top product FAS Primary Antibody
  • 应用备注
    FAS (N-145) antibody can be used for the detection of FAS (N-145) by Western blot, may also work for IHC and ICC.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Phosphate-Buffered Saline. No preservatives added.
    储存液
    Without preservative
    注意事项
    As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
    储存条件
    4 °C/-20 °C
    储存方法
    FAS antibody can be stored at 4 °C for short term (weeks). Long term storage should be at -20 °C.
  • 抗原
    FAS (TNF Receptor Superfamily, Member 6 (FAS))
    别名
    FAS (FAS 产品)
    别名
    ALPS1A antibody, APO-1 antibody, APT1 antibody, CD95 antibody, FAS1 antibody, FASTM antibody, TNFRSF6 antibody, AI196731 antibody, APO1 antibody, TNFR6 antibody, Tnfrsf6 antibody, lpr antibody, Fas cell surface death receptor antibody, Fas (TNF receptor superfamily member 6) antibody, FAS antibody, Fas antibody, fas antibody
    背景
    Tumor necrosis factor receptor superfamily, member 6 isoform 1, apoptosis antigen 1, Fas antigen, APO-1 cell surface antigen. This protein is a member of the TNF-receptor superfamily. This receptor contains a death domain. It has been shown to play a central role in the physiological regulation of programmed cell death, and has been implicated in the pathogenesis of various malignancies and diseases of the immune system. The interaction of this receptor with its ligand allows the formation of a death-inducing signaling complex that includes Fas-associated death domain protein (FADD), caspase 8, and caspase 10. The autoproteolytic processing of the caspases in the complex triggers a downstream caspase cascade, and leads to apoptosis. This receptor has been also shown to activate NF-κ,B, MAPK3/ERK1, and MAPK8/JNK, and is found to be involved in transducing the proliferating signals in normal diploid fibroblast and T cells. At least eight alternatively spliced transcript variants encoding seven distinct isoforms have been described. The isoforms lacking the transmembrane domain may negatively regulate the apoptosis mediated by the full length isoform. ** Cat.N
    分子量
    37.7 kDa (calculated)
    基因ID
    355
    NCBI登录号
    NP_000034
    UniProt
    P25445
    途径
    p53 Pathway, Apoptosis, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity
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