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FAS 抗体 (AA 150-250)

FAS 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3020739
发货至: 中国
  • 抗原 See all FAS 抗体
    FAS (TNF Receptor Superfamily, Member 6 (FAS))
    抗原表位
    • 25
    • 16
    • 16
    • 8
    • 8
    • 6
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 150-250
    适用
    • 213
    • 67
    • 62
    • 19
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    宿主
    • 158
    • 89
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    克隆类型
    • 155
    • 100
    • 1
    多克隆
    标记
    • 123
    • 27
    • 25
    • 12
    • 10
    • 7
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FAS antibody is un-conjugated
    应用范围
    • 164
    • 117
    • 74
    • 65
    • 36
    • 35
    • 31
    • 26
    • 26
    • 20
    • 19
    • 9
    • 8
    • 6
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    序列
    EHGIIKECTL TSNTKCKEEG SRSNLGWLCL LLLPIPLIVW VKRKEVQKTC RKHRKENQGS HESPTLNPET VAINLSDVDL SKYITTIAGV MTLSQVKGFV R
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Polyclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    A synthetic peptide corresponding to a sequence within amino acids 150-250 of human Fas (NP_000034.1).
    亚型
    IgG
  • 应用备注
    WB,1:500 - 1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid freeze / thaw cycles
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • Wang, Yan, Xiao, Zhou, Liu, Zeng, Liu, Li, Yuan, Wu, Yi, Razack, Wen: "Anti-obesity effect of a traditional Chinese dietary habit-blending lard with vegetable oil while cooking." in: Scientific reports, Vol. 7, Issue 1, pp. 14689, (2017) (PubMed).

    Chen, Gu, Jiang, Zhang: "Nuclear translocation of nuclear factor kappa B is regulated by G protein signaling pathway in arsenite-induced apoptosis in HBE cell line." in: Environmental toxicology, (2015) (PubMed).

    Gu, Chen, Jiang, Zhang: "Resveratrol Synergistically Triggers Apoptotic Cell Death with Arsenic Trioxide via Oxidative Stress in Human Lung Adenocarcinoma A549 Cells." in: Biological trace element research, Vol. 163, Issue 1-2, pp. 112-23, (2015) (PubMed).

    Chen, Jiang, Lai, Liu, Zhang: "Resveratrol protects against arsenic trioxide-induced oxidative damage through maintenance of glutathione homeostasis and inhibition of apoptotic progression." in: Environmental and molecular mutagenesis, (2014) (PubMed).

  • 抗原
    FAS (TNF Receptor Superfamily, Member 6 (FAS))
    别名
    FAS (FAS 产品)
    别名
    ALPS1A antibody, APO-1 antibody, APT1 antibody, CD95 antibody, FAS1 antibody, FASTM antibody, TNFRSF6 antibody, AI196731 antibody, APO1 antibody, TNFR6 antibody, Tnfrsf6 antibody, lpr antibody, Fas cell surface death receptor antibody, Fas (TNF receptor superfamily member 6) antibody, FAS antibody, Fas antibody, fas antibody
    背景
    The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains a death domain. It has been shown to play a central role in the physiological regulation of programmed cell death, and has been implicated in the pathogenesis of various malignancies and diseases of the immune system. The interaction of this receptor with its ligand allows the formation of a death-inducing signaling complex that includes Fas-associated death domain protein (FADD), caspase 8, and caspase 10. The autoproteolytic processing of the caspases in the complex triggers a downstream caspase cascade, and leads to apoptosis. This receptor has been also shown to activate NF-kappaB, MAPK3/ERK1, and MAPK8/JNK, and is found to be involved in transducing the proliferating signals in normal diploid fibroblast and T cells. Several alternatively spliced transcript variants have been described, some of which are candidates for nonsense-mediated mRNA decay (NMD). The isoforms lacking the transmembrane domain may negatively regulate the apoptosis mediated by the full length isoform.,ALPS1A,APO-1,APT1,CD95,FAS1,FASTM,TNFRSF6,FAS,Cell Biology & Developmental Biology,Apoptosis,Mitochondrial Control of Apoptosis,Inhibition of Apoptosis,Death Receptor Signaling Pathway,Immunology & Inflammation,CD markers,Cytokines,TNF,Cell Intrinsic Innate Immunity Signaling Pathway,Neuroscience,Neurodegenerative Diseases,FAS
    分子量
    9 kDa/11 kDa/14 kDa/16 kDa/24 kDa/35 kDa/37 kDa
    基因ID
    355
    UniProt
    P25445
    途径
    p53 Pathway, Apoptosis, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity
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