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CD59 抗体

CD59 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2434430
发货至: 中国
  • 抗原 See all CD59 抗体
    CD59
    适用
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    宿主
    • 90
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    克隆类型
    • 97
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    多克隆
    标记
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    This CD59 antibody is un-conjugated
    应用范围
    • 101
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    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    纯化方法
    Affinity purification
    免疫原
    Synthetic peptide of human CD59
    亚型
    IgG
    Top Product
    Discover our top product CD59 Primary Antibody
  • 应用备注
    WB 1:500-1:2000, IHC 1:100-1:300
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.5 mg/mL
    缓冲液
    PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
    储存液
    Sodium azide
    注意事项
    Avoid freeze / thaw cycles.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    CD59
    别名
    CD59 (CD59 产品)
    别名
    16.3A5 antibody, 1F5 antibody, EJ16 antibody, EJ30 antibody, EL32 antibody, G344 antibody, HRF-20 antibody, HRF20 antibody, MAC-IP antibody, MACIF antibody, MEM43 antibody, MIC11 antibody, MIN1 antibody, MIN2 antibody, MIN3 antibody, MIRL antibody, MSK21 antibody, p18-20 antibody, Cd59a antibody, Cd59b antibody, MACIP antibody, CD59 molecule (CD59 blood group) antibody, CD59 molecule antibody, CD59 antibody, Cd59 antibody
    背景
    This gene encodes a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. This protein also plays a role in signal transduction pathways in the activation of T cells. Mutations in this gene cause CD59 deficiency, a disease resulting in hemolytic anemia and thrombosis, and which causes cerebral infarction.
    分子量
    Calculated MW: 14 kDa
    NCBI登录号
    NP_000602
    途径
    Complement System
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